In vitro and in vivo optimized reconstruction for low-keV virtual monoenergetic photon-counting detector CT angiography of lower legs

dc.contributor.authorGraafen, Dirk
dc.contributor.authorBart, Willi
dc.contributor.authorHalfmann, Moritz C.
dc.contributor.authorMüller, Lukas
dc.contributor.authorHobohm, Lukas
dc.contributor.authorYang, Yang
dc.contributor.authorNeufang, Achim
dc.contributor.authorEspinola-Klein, Christine
dc.contributor.authorPitton, Michael B.
dc.contributor.authorKloeckner, Roman
dc.contributor.authorVarga-Szemes, Akos
dc.contributor.authorEmrich, Tilman
dc.date.accessioned2024-12-10T15:03:27Z
dc.date.available2024-12-10T15:03:27Z
dc.date.issued2024
dc.description.abstractBackground: Lower extremity peripheral artery disease frequently presents with calcifications which reduces the accuracy of computed tomography (CT) angiography, especially below-the-knee. Photon-counting detector (PCD)-CT offers improved spatial resolution and less calcium blooming. We aimed to identify the optimal reconstruction parameters for PCD-CT angiography of the lower legs. Methods: Tubes with different diameters (1–5 mm) were filled with different iodine concentrations and scanned in a water container. Images were reconstructed with 0.4 mm isotropic resolution using a quantitative kernel at all available sharpness levels (Qr36 to Qr76) and using different levels of quantum iterative reconstruction (QIR-2–4). Noise and image sharpness were determined for all reconstructions. Additionally, CT angiograms of 20 patients, reconstructed with a medium (Qr44), sharp (Qr60), and ultrasharp (Qr72) kernel at QIR-2-4, were evaluated by three readers assessing noise, delineation of plaques and vessel walls, anden_GB
dc.identifier.doihttp://doi.org/10.25358/openscience-11089
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/11108
dc.language.isoengde
dc.rightsCC-BY-4.0*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleIn vitro and in vivo optimized reconstruction for low-keV virtual monoenergetic photon-counting detector CT angiography of lower legsen_GB
dc.typeZeitschriftenaufsatzde
jgu.journal.titleEuropean radiology experimentalde
jgu.journal.volume8de
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.nameJohannes Gutenberg-Universität Mainz
jgu.organisation.number2700
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.alternative89de
jgu.publisher.doi10.1186/s41747-024-00481-xde
jgu.publisher.issn2509-9280de
jgu.publisher.nameSpringerde
jgu.publisher.placeChamde
jgu.publisher.year2024
jgu.rights.accessrightsopenAccess
jgu.subject.ddccode610de
jgu.subject.dfgLebenswissenschaftende
jgu.type.contenttypeScientific articlede
jgu.type.dinitypeArticleen_GB
jgu.type.resourceTextde
jgu.type.versionPublished versionde

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