Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-8588
Authors: | Thiem, Daniel G. E. Siegberg, Fabia Römer, Paul Blatt, Sebastian Pabst, Andreas Heimes, Diana Al-Nawas, Bilal Kämmerer, Peer W. |
Title: | Long-term donor site morbidity and flap perfusion following Radial versus Ulnar Forearm Free Flap : a randomized controlled prospective clinical trial |
Online publication date: | 19-Jan-2023 |
Year of first publication: | 2022 |
Language: | english |
Abstract: | This clinical prospective randomized controlled study aimed to investigate the differences between Radial (RFFF) and Ulnar (UFFF) Forearm Free Flap in terms of success, performance, and donor site morbidity. Thirty patients with reconstruction of the head and neck region were included. For the first time, this study assessed flap-perfusion characteristics, donor-site-wound-healing dynamics and hand perfusion using hyperspectral imaging. Further, subjective (Likert-scale, DASH-score) and objective (grip/pinch-strength) parameters of donor site morbidity were analysed. Postoperative follow-up was performed until 6 months after index surgery. With 100% of patients, RFFF and UFFF were equally successful. Compared to surrounding reference, UFFF revealed significant lower tissue oxygenation saturation (StO2) than RFFF. Compared with UFFF, blood flow in both the thenar and hypothenar region were significantly reduced 6 months following RFFF transfer. After four weeks, 27% more patients demonstrated impaired wound healing following RFFF transfer. After 6 months, epithelial-surface continuity was restored in all patients of both groups. After 6 months, overall rates of both subjective and objective donor site morbidity were comparable between RFFF and UFFF. RFFF and UFFF both demonstrate similar success rates and HSI-perfusion dynamics following transfer. After 4 weeks, wound-healing disorder appeared significantly more often in RFFF than in UFFF; however, they became equal after 6 months. RFFF and UFFF can be considered as mutual alternatives. Keywords: RFFF; UFFF; reconstruction; head and neck; hyperspectral imaging; HSI; randomized controlled prospective study; free flap; donor site morbidity |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-8588 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
Document type specification: | Scientific article |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | Journal of Clinical Medicine 11 13 |
Pages or article number: | 3601 |
Publisher: | MDPI |
Publisher place: | Basel |
Issue date: | 2022 |
ISSN: | 2077-0383 |
Publisher DOI: | 10.3390/jcm11133601 |
Appears in collections: | DFG-491381577-G |
Files in This Item:
File | Description | Size | Format | ||
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![]() | longterm_donor_site_morbidity-20230119094323823.pdf | 1.29 MB | Adobe PDF | View/Open |