Authors:	Gleede, Barbara Selt, Maximilian Franke, Robert Waldvogel, Siegfried R.
Title:	Developments in the dehydrogenative electrochemical synthesis of 3,3′,5,5′-tetramethyl-2,2′-biphenol
Online publication date:	17-Nov-2022
Year of first publication:	2021
Language:	english
Abstract:	The symmetric biphenol 3,3′,5,5′-tetramethyl-2,2′-biphenol is a well-known ligand building block and is used in transition-metal catalysis. In the literature, there are several synthetic routes for the preparation of this exceptional molecule. Herein, the focus is on the sustainable electrochemical synthesis of 3,3′,5,5′-tetramethyl-2,2′-biphenol. A brief overview of the developmental history of this inconspicuous molecule, which is of great interest for technical applications, but has many challenges for its synthesis, is provided. The electro-organic method is a powerful, sustainable, and efficient alternative to conventional synthesis to obtain this symmetric biphenol up to the kilogram scale. Another section of this article is devoted to different process management strategies in batch-type and flow electrolysis and their respective advantages.
DDC:	540 Chemie 540 Chemistry and allied sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 09 Chemie, Pharmazie u. Geowissensch.
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8160
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	Chemistry - a European journal 27 32
Pages or article number:	8252 8263
Publisher:	Wiley-VCH
Publisher place:	Weinheim
Issue date:	2021
ISSN:	1521-3765
Publisher DOI:	10.1002/chem.202005197
Appears in collections:	JGU-Publikationen