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Authors: Häring, Andreas Peter
Pollok, Dennis
Strücker, Benjamin R.
Kilian, Vincent
Schneider, Johannes
Waldvogel, Siegfried R.
Title: Beyond Kolbe and Hofer–Moest : electrochemical synthesis of carboxylic anhydrides from carboxylic acids
Online publication date: 28-Oct-2022
Year of first publication: 2022
Language: english
Abstract: Herein we report a conceptually new non-decarboxylative electrolysis of carboxylic acids to obtain their corresponding anhydrides as highly valuable reagents in organic synthesis. All carbon atoms of the starting material are preserved in the product in an overall redox-neutral reaction. In a broad substrate scope of carboxylic acids the anhydrides are generated with high selectivity, which demonstrates the versatility of the developed method. Beneficially, no dehydrating reagents are required in comparison to conventional methods and the synthesis is based on uncritical starting materials using graphite and stainless steel as very inexpensive and eco-friendly electrode materials.
DDC: 540 Chemie
540 Chemistry and allied sciences
Institution: Johannes Gutenberg-Universität Mainz
Department: FB 09 Chemie, Pharmazie u. Geowissensch.
Place: Mainz
Version: Published version
Publication type: Zeitschriftenaufsatz
Document type specification: Scientific article
License: CC BY-NC-ND
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Journal: ChemistryOpen
Pages or article number: e202200059
Publisher: Wiley-VCH-Verlag
Publisher place: Weinheim
Issue date: 2022
ISSN: 2191-1363
Publisher DOI: 10.1002/open.202200059
Appears in collections:DFG-491381577-G

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