Authors:	Klein, Martin Waldvogel, Siegfried R.
Title:	Anodic dehydrogenative cyanamidation of thioethers : simple and sustainable synthesis of N-cyanosulfilimines
Online publication date:	8-Nov-2022
Year of first publication:	2021
Language:	english
Abstract:	A novel and very simple to perform electrochemical approach for the synthesis of several N-cyanosulfilimines in good to excellent yields was established. This method provides access to biologically relevant sulfoximines by consecutive oxidation using electro-generated periodate. This route can be easily scaled-up to gram quantities. The S,N coupling is carried out at an inexpensive carbon anode by direct oxidation of sulfide. Therefore, the designed process is atom economic and represents a new “green route” for the synthesis of sulfilimines and sulfoximines.
DDC:	540 Chemie 540 Chemistry and allied sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 09 Chemie, Pharmazie u. Geowissensch.
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8037
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	Angewandte Chemie : international edition 60 43
Pages or article number:	23197 23201
Publisher:	Wiley-VCH
Publisher place:	Weinheim
Issue date:	2021
ISSN:	1521-3773
Publisher DOI:	10.1002/anie.202109033
Appears in collections:	JGU-Publikationen