Authors:	Stach, Oliver S. Breul, Katharina Berač, Christian M. Urschbach, Moritz Seiffert, Sebastian Besenius, Pol
Title:	Bridging rigidity and flexibility : modulation of supramolecular hydrogels by metal complexation
Online publication date:	27-Oct-2022
Year of first publication:	2022
Language:	english
Abstract:	The combination of complementary, noncovalent interactions is a key principle for the design of multistimuli responsive hydrogels. In this work, an amphiphilic peptide, supramacromolecular hydrogelator which combines metal-ligand coordination induced gelation and thermoresponsive toughening is reported. Following a modular approach, the incorporation of the triphenylalanine sequence FFF into a structural (C3EG) and a terpyridine-functionalized (C3Tpy) C3-symmetric monomer enables their statistical copolymerization into self-assembled, 1D nanorods in water, as investigated by circular dichroism (CD) spectroscopy and transmission electron microscopy (TEM). In the presence of a terpyridine functionalized telechelic polyethylene glycol (PEG) cross-linker, complex formation upon addition of different transition metal ions (Fe2+, Zn2+, Ni2+) induces the formation of soft, reversible hydrogels at a solid weight content of 1 wt% as observed by linear shear rheology. The viscoelastic behavior of Fe2+ and Zn2+ cross-linked hydrogels are basically identical, while the most kinetically inert Ni2+ coordinative bond leads to significantly weaker hydrogels, suggesting that the most dynamic rather than the most thermodynamically stable interaction supports the formation of robust and responsive hydrogel materials.
DDC:	540 Chemie 540 Chemistry and allied sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 09 Chemie, Pharmazie u. Geowissensch.
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8034
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY
Information on rights of use:	https://creativecommons.org/licenses/by/4.0/
Journal:	Macromolecular rapid communications 43 12
Pages or article number:	2100473
Publisher:	Wiley-VCH
Publisher place:	Weinheim
Issue date:	2022
ISSN:	1521-3927
Publisher DOI:	10.1002/marc.202100473
Appears in collections:	JGU-Publikationen