Authors:	Schepers, Jana Behl, Christian
Title:	Lipid droplets and autophagy : links and regulations from yeast to humans
Online publication date:	12-Sep-2022
Year of first publication:	2021
Language:	english
Abstract:	Recent advances in the yeast Saccharomyces cerevisiae and higher eukaryotes have been increasingly connecting lipid droplet (LD) dynamics to the regulation of autophagy. In this review we will discuss implications that connect LD de novo synthesis and LD mobilization to autophagy and how autophagy is regulated by these mechanisms. Elucidating these connections might pose a chance to further understand autophagy induction and membrane biogenesis for the growing autophagosome under different conditions. Increasing our understanding of these mechanisms might provide a chance to understand several conditions that might be related to LD dysregulation and, possibly, as a consequence of this, dysregulation of autophagy.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-7717
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY
Information on rights of use:	https://creativecommons.org/licenses/by/4.0/
Journal:	Journal of cellular biochemistry 122 6
Pages or article number:	602 611
Publisher:	Wiley-Liss
Publisher place:	New York, NY
Issue date:	2021
ISSN:	1097-4644
Publisher DOI:	10.1002/jcb.29889
Appears in collections:	JGU-Publikationen