Authors:	Baier, Bernhard Cuvenhaus, Hannah Müller, Notger Birklein, Frank Dieterich, Marianne
Title:	Vestibular compensation of otolith graviceptive dysfunction in stroke patients
Online publication date:	5-Sep-2022
Year of first publication:	2022
Language:	english
Abstract:	Background and purpose A sensitive and frequent clinical sign of a vestibular tone imbalance is the tilt of the perceived subjective visual vertical (SVV). There are no data yet focusing on lesion location at the cortical level as a factor for predicting compensation from the tilt of the SVV. Methods With modern voxelwise lesion behavior mapping analysis, the present study determines whether lesion location in 23 right-hemispheric cortical stroke patients with an otolith dysfunction could predict the compensation of a vestibular tone imbalance in the chronic stage. Results Our statistical anatomical lesion analysis revealed that lesions of the posterior insular cortex are involved in vestibular otolith compensation. Conclusion The insular cortex appears to be a critical anatomical region for predicting a tilt of the SVV as a chronic disorder in stroke patients.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-7676
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	European journal of immunology 29 3
Pages or article number:	905 909
Publisher:	Wiley-Blackwell
Publisher place:	Oxford u.a.
Issue date:	2022
ISSN:	1468-1331
Publisher DOI:	10.1111/ene.15193
Appears in collections:	JGU-Publikationen