Gutenberg Open Science: Hearing loss and its burden of disease in a large German cohort

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7674

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DC Field	Value	Language
dc.contributor.author	Hackenberg, Berit	-
dc.contributor.author	Döge, Julia	-
dc.contributor.author	Lackner, Karl J.	-
dc.contributor.author	Beutel, Manfred E.	-
dc.contributor.author	Münzel, Thomas	-
dc.contributor.author	Pfeiffer, Norbert	-
dc.contributor.author	Nagler, Markus	-
dc.contributor.author	Schmidtmann, Irene	-
dc.contributor.author	Wild, Philipp S.	-
dc.contributor.author	Matthias, Christoph	-
dc.contributor.author	Bahr, Katharina	-
dc.date.accessioned	2022-09-05T09:07:23Z	-
dc.date.available	2022-09-05T09:07:23Z	-
dc.date.issued	2022	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7689	-
dc.description.abstract	Objectives/Hypothesis Hearing loss is the most common sensory impairment worldwide. It restricts patients in many aspects of their daily lives and can lead to social exclusion. Understanding this burden is a mandatory requirement for the care of those affected. Therefore, the aim of this study was to estimate the burden of hearing loss in a large German cohort. Study Design Cohort study. Methods The Gutenberg Health Study is designed as a single-center, prospective, and observational cohort study and representative for the city of Mainz, Germany, with its district. Participants were interviewed concerning common otologic symptoms and tested by pure-tone audiometry. The primary outcome was hearing impairment stratified by age and sex. The prevalence of tinnitus was estimated for a subcohort to calculate disability-adjusted life years (DALYs). All results were weighted by the European Standard Population (ESP) 2013. Results A total of 5,024 participants (mean age: 61.2 years, 2,591 men and 2,433 women) were included in the study. Hearing impairment showed the following prevalence: 28.2% (95% confidence interval [CI], 26.9%–29.4%) mild impairment, 10.1% (95% CI, 9.3%–11.0%) moderate impairment, 2.3% (95% CI, 1.9%–2.7%) moderately severe impairment, 0.2% (95% CI, 0.1%–0.4%) severe impairment, 0% (95% CI, 0.0%–0.1%) profound impairment, and 0.1% (95% CI, 0.0%–0.2%) complete impairment. Weighted for the ESP 2013 (all ages), hearing impairment across all levels (with/without tinnitus) causes a total of 2,118.97 DALYs per 100,000. Conclusion With 40.9% affected, the hearing loss represents a relevant burden of the German population. Understanding this will provide the basis for future guidelines on how to care for these patients.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC-ND	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Hearing loss and its burden of disease in a large German cohort—hearing loss in Germany	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7674	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	The laryngoscope	de
jgu.journal.volume	132	de
jgu.journal.issue	9	de
jgu.pages.start	1843	de
jgu.pages.end	1849	de
jgu.publisher.year	2022	-
jgu.publisher.name	Wiley	de
jgu.publisher.place	Malden, MA	de
jgu.publisher.issn	1531-4995	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1002/lary.29980	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	JGU-Publikationen

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