Gutenberg Open Science: Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7579

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DC Field	Value	Language
dc.contributor.author	Siggelkow, Wulf	-
dc.contributor.author	Boehm, Daniel	-
dc.contributor.author	Gebhard, Susanne	-
dc.contributor.author	Battista, Marco	-
dc.contributor.author	Sicking, Isabel	-
dc.contributor.author	Lebrecht, Antje	-
dc.contributor.author	Solbach, Christine	-
dc.contributor.author	Hellwig, Birte	-
dc.contributor.author	Rahnenfuhrer, Jorg	-
dc.contributor.author	Koelbl, Heinz	-
dc.contributor.author	Gehrmann, Mathias	-
dc.contributor.author	Marchan, Rosemarie	-
dc.contributor.author	Cadenas, Cristina	-
dc.contributor.author	Hengstler, Jan G.	-
dc.contributor.author	Schmidt, Marcus	-
dc.date.accessioned	2022-08-19T10:06:33Z	-
dc.date.available	2022-08-19T10:06:33Z	-
dc.date.issued	2012	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7593	-
dc.description.abstract	BACKGROUND: Inhibitors targeting the cell cycle-regulated aurora kinase A (AURKA) are currently being developed. Here, we examine the prognostic impact of AURKA in node-negative breast cancer patients without adjuvant systemic therapy (n = 766). METHODS: AURKA was analyzed using microarray-based gene-expression data from three independent cohorts of node-negative breast cancer patients. In multivariate Cox analyses, the prognostic impact of age, histological grade, tumor size, estrogen receptor (ER), and HER2 were considered. RESULTS: Patients with higher AURKA expression had a shorter metastasis-free survival (MFS) in the	en_GB
dc.description.sponsorship	DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin	de
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/2.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7579	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	BMC cancer	de
jgu.journal.volume	12	de
jgu.pages.alternative	Art. 562	de
jgu.publisher.year	2012	-
jgu.publisher.name	Springer	de
jgu.publisher.place	London	de
jgu.publisher.uri	http://dx.doi.org/10.1186/1471-2407-12-562	de
jgu.publisher.issn	1471-2407	de
jgu.organisation.place	Mainz	-
jgu.identifier.pmid	23186136	-
jgu.subject.ddccode	610	de
opus.date.modified	2015-09-17T09:36:57Z	-
opus.subject.dfgcode	04-205	-
opus.organisation.string	FB 04: Medizin: Klinik und Poliklinik für Geburtshilfe und Frauenkrankheiten	de_DE
opus.identifier.opusid	23651	-
opus.importsource	pubmed	-
opus.institute.number	0445	-
opus.metadataonly	false	-
opus.type.contenttype	Keine	de_DE
opus.type.contenttype	None	en_EN
opus.affiliated	Battista, Marco	-
opus.affiliated	Sicking, Isabel	-
opus.affiliated	Lebrecht, Antje	-
opus.affiliated	Solbach, Christine	-
opus.affiliated	Schmidt, Marcus	-
jgu.publisher.doi	10.1186/1471-2407-12-562	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	DFG-OA-Publizieren (2012 - 2017)

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