Straightforward electrochemical sulfonylation of arenes and aniline derivatives using sodium sulfinates

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Abstract

We present a general electrochemical synthesis of sulfones from arenes and aniline derivatives with sodium sulfinates. A wide range of C−S cross-coupling products is available by this oxidant- and transition metal-free method. Both aryl and diaryl sulfones can be readily obtained, using this scalable and inherently safe one-step protocol. Since the synthesis excludes the need for additional supporting electrolyte and occurs in an aqueous electrolyte system that is easily recovered and recycled, this strategy represents a sustainable and green alternative to existing sulfonylation reactions.

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ChemElectroChem, 6, 17, Wiley-VCH, Weinheim, 2019, https://doi.org/10.1002/celc.201901212

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