Authors:	Wirtanen, Tom Rodrigo, Eduardo Waldvogel, Siegfried R.
Title:	Selective and scalable electrosynthesis of 2H-2-(aryl)-benzo[d]-1,2,3-triazoles and their N-oxides by using leaded bronze cathodes
Online publication date:	11-Aug-2021
Year of first publication:	2020
Language:	english
Abstract:	Electrosynthesis of 2H-2-(aryl)benzo[d]-1,2,3-triazoles and their N-oxides from 2-nitroazobenzene derivatives is reported. The electrolysis is conducted in a very simple undivided cell under constant current conditions with a leaded bronze cathode and a glassy carbon anode. The product distribution between 2H-2-(aryl)benzo[d]-1,2,3-triazoles and their N-oxides can be guided by simply controlling the current density and the amount of the charge applied. The reaction tolerates several sensitive functional groups in reductive electrochemistry. The usefulness and the applicability of the synthetic method is demonstrated by a formal synthesis of an antiviral compound.
DDC:	540 Chemie 540 Chemistry and allied sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 09 Chemie, Pharmazie u. Geowissensch.
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-6258
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	Chemistry - a European journal 26 25
Pages or article number:	5592 5597
Publisher:	Wiley-VCH
Publisher place:	Weinheim
Issue date:	2020
ISSN:	1521-3765
Publisher URL:	https://doi.org/10.1002/chem.201905874
Publisher DOI:	10.1002/chem.201905874
Appears in collections:	JGU-Publikationen