Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-6254
Authors: | Arndt, Sebastian Weis, Dominik Donsbach, Kai Waldvogel, Siegfried R. |
Title: | The “green” electrochemical synthesis of periodate |
Online publication date: | 9-Aug-2021 |
Year of first publication: | 2020 |
Language: | english |
Abstract: | High-grade periodate is relatively expensive, but is required for many sensitive applications such as the synthesis of active pharmaceutical ingredients. These high costs originate from using lead dioxide anodes in contemporary electrochemical methods and from expensive starting materials. A direct and cost-efficient electrochemical synthesis of periodate from iodide, which is less costly and relies on a readily available starting material, is reported. The oxidation is conducted at boron-doped diamond anodes, which are durable, metal-free, and nontoxic. The avoidance of lead dioxide ultimately lowers the cost of purification and quality assurance. The electrolytic process was optimized by statistical methods and was scaled up in an electrolysis flow cell that enhanced the space–time yields by a cyclization protocol. An LC-PDA analytical protocol was established enabling simple quantification of iodide, iodate, and periodate simultaneously with remarkable precision. |
DDC: | 540 Chemie 540 Chemistry and allied sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 09 Chemie, Pharmazie u. Geowissensch. |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-6254 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY-NC |
Information on rights of use: | https://creativecommons.org/licenses/by-nc/4.0/ |
Journal: | Angewandte Chemie 59 21 |
Pages or article number: | 8036 8041 |
Publisher: | Wiley-VCH |
Publisher place: | Weinheim |
Issue date: | 2020 |
ISSN: | 1521-3773 |
Publisher URL: | https://doi.org/10.1002/anie.202002717 |
Publisher DOI: | 10.1002/anie.202002717 |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
---|---|---|---|---|---|
![]() | dr._arndt_sebastian-the_“green”_el-20210804145458267.pdf | 1.41 MB | Adobe PDF | View/Open |