Gutenberg Open Science: α-aminonitriles : from sustainable preparation to applications in natural product synthesis

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6229

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DC Field	Value	Language
dc.contributor.author	Grundke, Caroline	-
dc.contributor.author	Vierengel, Nina	-
dc.contributor.author	Opatz, Till	-
dc.date.accessioned	2021-08-03T07:56:29Z	-
dc.date.available	2021-08-03T07:56:29Z	-
dc.date.issued	2020	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/6239	-
dc.description.abstract	Due to their numerous reactivity modes, α-aminonitriles represent versatile and valuable building blocks in organic total synthesis. Since their discovery by Adolph Strecker in 1850, this compound class has seen a wide dissemination in synthetic applications from laboratory to million-ton industrial scale and was extensively used in the syntheses of various classes of natural products. As these compounds provide a multitude of reactivity options, we feel that a broad overview of their multiple reaction modes may reveal less familiar opportunities for successful total synthesis planning. This personal account article will thus focus on α-aminonitriles used as key intermediates in selected natural product synthesis sequences which have been reported in the two decades since Enders’ and Shilvock's seminal review. Natural α-aminonitriles will also briefly be treated.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC-ND	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject.ddc	540 Chemie	de_DE
dc.subject.ddc	540 Chemistry and allied sciences	en_GB
dc.title	α-aminonitriles : from sustainable preparation to applications in natural product synthesis	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-6229	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 09 Chemie, Pharmazie u. Geowissensch.	de
jgu.organisation.number	7950	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	The chemical record	de
jgu.journal.volume	20	de
jgu.journal.issue	9	de
jgu.pages.start	989	de
jgu.pages.end	1016	de
jgu.publisher.year	2020	-
jgu.publisher.name	Wiley	de
jgu.publisher.place	New York, NY u.a.	de
jgu.publisher.uri	https://doi.org/10.1002/tcr.202000066	de
jgu.publisher.issn	1528-0691	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	540	de
jgu.publisher.doi	10.1002/tcr.202000066
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

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