Gutenberg Open Science: Predictors of short- and long-term outcomes of patients undergoing transcatheter mitral valve edge-to-edge repair

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6228

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DC Field	Value	Language
dc.contributor.author	Geyer, Martin	-
dc.contributor.author	Keller, Karsten	-
dc.contributor.author	Born, Sonja	-
dc.contributor.author	Bachmann, Kevin	-
dc.contributor.author	Tamm, Alexander R.	-
dc.contributor.author	Ruf, Tobias F.	-
dc.contributor.author	Kreidel, Felix	-
dc.contributor.author	Hahad, Omar	-
dc.contributor.author	Ahoopai, Majid	-
dc.contributor.author	Hobohm, Lukas	-
dc.contributor.author	Beiras-Fernandez, Andres	-
dc.contributor.author	Kornberger, Angela	-
dc.contributor.author	Schulz, Eberhard	-
dc.contributor.author	Münzel, Thomas	-
dc.contributor.author	Bardeleben, Ralph Stephan von	-
dc.date.accessioned	2021-08-02T11:05:42Z	-
dc.date.available	2021-08-02T11:05:42Z	-
dc.date.issued	2021	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/6238	-
dc.description.abstract	OBJECTIVES Transcatheter mitral valve repair (TMVR) by edge-to-edge therapy is an established treatment for severe mitral valve regurgitation (MR). BACKGROUND Symptomatic and prognostic benefit in functional MR has been shown recently; nevertheless, data on long-term outcomes are sparse. METHODS AND RESULTS We analyzed survival of patients treated with isolated edge-to-edge repair from June 2010 to March 2018 (primarily combined edge-to-edge repair with other mitral valve interventions was excluded) in a retrospective monocentric study. Overall, 627 consecutive patients (47.0% females, 78.6 years in mean) were included. Leading etiology was functional MR (57.4%). Follow-up regarding survival was available in 97.0%. While 97.6% were discharged alive, 75.7% were alive after a 1-year, 54.5% after 3-year, 37.6% after 5-year and 21.7% after 7-year follow-up. Higher logistic Euroscores and comorbidities such as COPD and renal insufficiency were associated with higher in-hospital and 1-year mortality. Importantly, in-hospital survival increased over the years. CONCLUSIONS With the present study we established high survival rates at discharge and after 1 year of patients treated with TMVR. This goes along with high implantation numbers, increased interventional experience and a better in-hospital survival over the years. Long-term mortality in turn was substantially influenced by comorbidities.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Predictors of short- and long-term outcomes of patients undergoing transcatheter mitral valve edge-to-edge repair	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-6228	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Catheterization and cardiovascular interventions	de
jgu.journal.volume	97	de
jgu.journal.issue	3	de
jgu.pages.start	E390	de
jgu.pages.end	E401	de
jgu.publisher.year	2021	-
jgu.publisher.name	Wiley Interscience	de
jgu.publisher.place	New York, NY	de
jgu.publisher.uri	https://doi.org/10.1002/ccd.29068	de
jgu.publisher.issn	1522-726X	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1002/ccd.29068	-
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	JGU-Publikationen

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