Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-6228
Authors: | Geyer, Martin Keller, Karsten Born, Sonja Bachmann, Kevin Tamm, Alexander R. Ruf, Tobias F. Kreidel, Felix Hahad, Omar Ahoopai, Majid Hobohm, Lukas Beiras-Fernandez, Andres Kornberger, Angela Schulz, Eberhard Münzel, Thomas Bardeleben, Ralph Stephan von |
Title: | Predictors of short- and long-term outcomes of patients undergoing transcatheter mitral valve edge-to-edge repair |
Online publication date: | 2-Aug-2021 |
Year of first publication: | 2021 |
Language: | english |
Abstract: | OBJECTIVES Transcatheter mitral valve repair (TMVR) by edge-to-edge therapy is an established treatment for severe mitral valve regurgitation (MR). BACKGROUND Symptomatic and prognostic benefit in functional MR has been shown recently; nevertheless, data on long-term outcomes are sparse. METHODS AND RESULTS We analyzed survival of patients treated with isolated edge-to-edge repair from June 2010 to March 2018 (primarily combined edge-to-edge repair with other mitral valve interventions was excluded) in a retrospective monocentric study. Overall, 627 consecutive patients (47.0% females, 78.6 years in mean) were included. Leading etiology was functional MR (57.4%). Follow-up regarding survival was available in 97.0%. While 97.6% were discharged alive, 75.7% were alive after a 1-year, 54.5% after 3-year, 37.6% after 5-year and 21.7% after 7-year follow-up. Higher logistic Euroscores and comorbidities such as COPD and renal insufficiency were associated with higher in-hospital and 1-year mortality. Importantly, in-hospital survival increased over the years. CONCLUSIONS With the present study we established high survival rates at discharge and after 1 year of patients treated with TMVR. This goes along with high implantation numbers, increased interventional experience and a better in-hospital survival over the years. Long-term mortality in turn was substantially influenced by comorbidities. |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-6228 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY-NC |
Information on rights of use: | https://creativecommons.org/licenses/by-nc/4.0/ |
Journal: | Catheterization and cardiovascular interventions 97 3 |
Pages or article number: | E390 E401 |
Publisher: | Wiley Interscience |
Publisher place: | New York, NY |
Issue date: | 2021 |
ISSN: | 1522-726X |
Publisher URL: | https://doi.org/10.1002/ccd.29068 |
Publisher DOI: | 10.1002/ccd.29068 |
Appears in collections: | JGU-Publikationen |
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