Gutenberg Open Science: Nanoparticles in the biological context : surface morphology and protein corona formation

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6179

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DC Field	Value	Language
dc.contributor.author	Richtering, Walter	-
dc.contributor.author	Alberg, Irina	-
dc.contributor.author	Zentel, Rudolf	-
dc.date.accessioned	2021-07-06T08:37:42Z	-
dc.date.available	2021-07-06T08:37:42Z	-
dc.date.issued	2020	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/6188	-
dc.description.abstract	A recent paper demonstrated that the formation of a protein corona is not a general property of all types of nanosized objects. In fact, it varies between a massive aggregation of plasma proteins onto the nanoparticle down to traces (e.g., a few proteins per 10 nanoparticles), which can only be determined by mass spectrometry in comparison to appropriate negative controls and background subtraction. Here, differences between various types of nanosized objects are discussed in order to determine general structure–property-relations from a physico-chemical viewpoint. It is highlighted that “not all nanoparticles are alike” and shown that their internal morphology, especially the difference between a strongly hydrated/swollen shell versus a sharp “hard” surface and its accessibility, is most relevant for biomedical applications.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject.ddc	540 Chemie	de_DE
dc.subject.ddc	540 Chemistry and allied sciences	en_GB
dc.title	Nanoparticles in the biological context : surface morphology and protein corona formation	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-6179	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 09 Chemie, Pharmazie u. Geowissensch.	de
jgu.organisation.number	7950	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Small	de
jgu.journal.volume	16	de
jgu.journal.issue	39	de
jgu.pages.alternative	2002162	de
jgu.publisher.year	2020	-
jgu.publisher.name	Wiley-VCH	de
jgu.publisher.place	Weinheim	de
jgu.publisher.uri	https://doi.org/10.1002/smll.202002162	de
jgu.publisher.issn	1613-6829	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	540	de
jgu.publisher.doi	10.1002/smll.202002162
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

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