Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6179
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dc.contributor.authorRichtering, Walter-
dc.contributor.authorAlberg, Irina-
dc.contributor.authorZentel, Rudolf-
dc.date.accessioned2021-07-06T08:37:42Z-
dc.date.available2021-07-06T08:37:42Z-
dc.date.issued2020-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/6188-
dc.description.abstractA recent paper demonstrated that the formation of a protein corona is not a general property of all types of nanosized objects. In fact, it varies between a massive aggregation of plasma proteins onto the nanoparticle down to traces (e.g., a few proteins per 10 nanoparticles), which can only be determined by mass spectrometry in comparison to appropriate negative controls and background subtraction. Here, differences between various types of nanosized objects are discussed in order to determine general structure–property-relations from a physico-chemical viewpoint. It is highlighted that “not all nanoparticles are alike” and shown that their internal morphology, especially the difference between a strongly hydrated/swollen shell versus a sharp “hard” surface and its accessibility, is most relevant for biomedical applications.en_GB
dc.language.isoengde
dc.rightsCC BY-NC*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.ddc540 Chemiede_DE
dc.subject.ddc540 Chemistry and allied sciencesen_GB
dc.titleNanoparticles in the biological context : surface morphology and protein corona formationen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-6179-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 09 Chemie, Pharmazie u. Geowissensch.de
jgu.organisation.number7950-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleSmallde
jgu.journal.volume16de
jgu.journal.issue39de
jgu.pages.alternative2002162de
jgu.publisher.year2020-
jgu.publisher.nameWiley-VCHde
jgu.publisher.placeWeinheimde
jgu.publisher.urihttps://doi.org/10.1002/smll.202002162de
jgu.publisher.issn1613-6829de
jgu.organisation.placeMainz-
jgu.subject.ddccode540de
jgu.publisher.doi10.1002/smll.202002162
Appears in collections:JGU-Publikationen

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