Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-5924
Authors: | Ruan, Yue Jiang, Subao Gericke, Adrian |
Title: | Age-related macular degeneration : role of oxidative stress and blood vessels |
Online publication date: | 31-May-2021 |
Year of first publication: | 2021 |
Language: | english |
Abstract: | Age-related macular degeneration (AMD) is a common irreversible ocular disease characterized by vision impairment among older people. Many risk factors are related to AMD and interact with each other in its pathogenesis. Notably, oxidative stress and choroidal vascular dysfunction were suggested to be critically involved in AMD pathogenesis. In this review, we give an overview on the factors contributing to the pathophysiology of this multifactorial disease and discuss the role of reactive oxygen species and vascular function in more detail. Moreover, we give an overview on therapeutic strategies for patients suffering from AMD. |
DDC: | 570 Biowissenschaften 570 Life sciences 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-5924 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
Document type specification: | Scientific article |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | International journal of molecular sciences 22 33 |
Pages or article number: | 1296 |
Publisher: | MDPI |
Publisher place: | Basel |
Issue date: | 2021 |
ISSN: | 1422-0067 1661-6596 |
Publisher URL: | https://doi.org/10.3390/ijms22031296 |
Publisher DOI: | 10.3390/ijms22031296 |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
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ruan_yue-age-related_ma-20210514135856710.pdf | 1.77 MB | Adobe PDF | View/Open |