Age-related macular degeneration : role of oxidative stress and blood vessels

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dc.contributor.authorRuan, Yue
dc.contributor.authorJiang, Subao
dc.contributor.authorGericke, Adrian
dc.date.accessioned2021-05-31T09:08:32Z
dc.date.available2021-05-31T09:08:32Z
dc.date.issued2021
dc.description.abstractAge-related macular degeneration (AMD) is a common irreversible ocular disease characterized by vision impairment among older people. Many risk factors are related to AMD and interact with each other in its pathogenesis. Notably, oxidative stress and choroidal vascular dysfunction were suggested to be critically involved in AMD pathogenesis. In this review, we give an overview on the factors contributing to the pathophysiology of this multifactorial disease and discuss the role of reactive oxygen species and vascular function in more detail. Moreover, we give an overview on therapeutic strategies for patients suffering from AMD.en_GB
dc.description.sponsorshipOpen Access-Publizieren Universität Mainz / Universitätsmedizin Mainz
dc.identifier.doihttp://doi.org/10.25358/openscience-5924
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/5933
dc.language.isoeng
dc.rightsCC-BY-4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc570 Biowissenschaftende_DE
dc.subject.ddc570 Life sciencesen_GB
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleAge-related macular degeneration : role of oxidative stress and blood vesselsen_GB
dc.typeZeitschriftenaufsatzde_DE
jgu.apc.price1787,80
jgu.journal.issue33
jgu.journal.titleInternational journal of molecular sciences
jgu.journal.volume22
jgu.organisation.departmentFB 04 Medizinde_DE
jgu.organisation.nameJohannes Gutenberg-Universität Mainzde_DE
jgu.organisation.number2700
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.alternative1296
jgu.publisher.doi10.3390/ijms22031296
jgu.publisher.issn1422-0067
jgu.publisher.issn1661-6596
jgu.publisher.nameMDPI
jgu.publisher.placeBasel
jgu.publisher.urihttps://doi.org/10.3390/ijms22031296
jgu.publisher.year2021
jgu.rights.accessrightsopenAccessen_GB
jgu.subject.ddccode570
jgu.subject.ddccode610
jgu.type.contenttypeScientific articleen_GB
jgu.type.dinitypeArticleen_GB
jgu.type.resourceTexten_GB
jgu.type.versionPublished versionen_GB

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