Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-5870
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dc.contributor.authorWild, Johannes-
dc.contributor.authorWenzel, Philip-
dc.date.accessioned2021-05-19T10:39:25Z-
dc.date.available2021-05-19T10:39:25Z-
dc.date.issued2021-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/5879-
dc.description.abstractAlthough essential hypertension affects a large proportion of the human population and is one of the key drivers of cardiovascular mortality worldwide, we still do not have a complete understanding of its pathophysiology. More than 50 years ago, the immune system has been identified as an important part of the pathogenesis of arterial hypertension. An exceeding variety of recent publications deals with the interplay between the numerous different components of the immune system and mechanisms of arterial hypertension and has substantially contributed to our understanding of the role of immunity and inflammation in the pathogenesis of the disease. In this review, we focus on myeloid cells and anatomical barriers as particular aspects of innate immunity in arterial hypertension. Since it represents a first line of defense protecting against pathogens and maintaining tissue homeostasis, innate immunity provides many mechanistic hinge points in the area of hypertension.en_GB
dc.language.isoengde
dc.rightsCC-BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleMyeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertensionen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-5870-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleJournal of molecular medicinede
jgu.journal.volume99de
jgu.pages.start315de
jgu.pages.end326de
jgu.publisher.year2021-
jgu.publisher.nameSpringerde
jgu.publisher.placeBerlin u.a.de
jgu.publisher.urihttps://doi.org/10.1007/s00109-020-02019-1de
jgu.publisher.issn1432-1440de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
Appears in collections:JGU-Publikationen

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