Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-5764
Authors: | Tschernatsch, Marlene Juenemann, Martin Alhaidar, Fouad El Shazly, Jasmin Butz, Marius Meyer, Marco Gerriets, Tibo Schönburg, Markus Schramm, Patrick |
Title: | Epileptic seizure discharges in patients after open chamber cardiac surgery : a prospective prevalence pilot study using continuous electroencephalography |
Online publication date: | 6-May-2021 |
Year of first publication: | 2020 |
Language: | english |
Abstract: | PURPOSE Patients undergoing cardiac surgery often develop delirium which increases the risk of postoperative morbidity and leads to a reduced quality of life. Retrospective studies show a higher incidence of delirium in patients with seizures. However, these studies do not systematically detect subclinical seizures, so the incidence of seizures after cardiac surgery remains speculative. The objective of this study is to determine the prevalence of electrographic seizures after elective open-chamber cardiac surgery. METHODS This prospective, blinded, monocentric, observational study investigated patients scheduled for elective open-chamber valve reconstruction or replacement. Anaesthesia, surgery and postoperative treatment were standardized and not influenced by the presented observation. After surgery, all patients arrived at the ICU, and EEG monitoring started within the first hour. EEG recording was continuously performed for up to 24 h, and the results were independently analysed by two blinded EEG board-certified neurologists. RESULTS 100 patients were included. Abnormal EEG patterns were present in 33% of patients, and 9% of all patients showed electrographic seizures. The main EEG activity at the beginning of each recording was suppressed or showed a burst-suppression pattern, and at the end of recording, all patients had an alpha/theta rhythm. An association between electrographic seizures and delirium was found (pχ2 < 0.01). CONCLUSION This study reveals a surprisingly high incidence of abnormal EEG patterns and electrographic seizures in patients undergoing open-chamber cardiac surgery. As electrographic seizures are associated with the incidence of delirium, this finding is a relevant phenomenon in the post-cardiac surgery ICU population. |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-5764 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY-NC |
Information on rights of use: | https://creativecommons.org/licenses/by-nc/4.0/ |
Journal: | Intensive care medicine 46 |
Pages or article number: | 1418 1424 |
Publisher: | Springer |
Publisher place: | Berlin u.a. |
Issue date: | 2020 |
ISSN: | 1432-1238 |
Publisher URL: | https://doi.org/10.1007/s00134-020-06073-8 |
Publisher DOI: | 10.1007/s00134-020-06073-8 |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
---|---|---|---|---|---|
schramm_patrick-epileptic_seiz-20210420100958452.pdf | 1.17 MB | Adobe PDF | View/Open |