Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-5764
Authors: Tschernatsch, Marlene
Juenemann, Martin
Alhaidar, Fouad
El Shazly, Jasmin
Butz, Marius
Meyer, Marco
Gerriets, Tibo
Schönburg, Markus
Schramm, Patrick
Title: Epileptic seizure discharges in patients after open chamber cardiac surgery : a prospective prevalence pilot study using continuous electroencephalography
Online publication date: 6-May-2021
Year of first publication: 2020
Language: english
Abstract: PURPOSE Patients undergoing cardiac surgery often develop delirium which increases the risk of postoperative morbidity and leads to a reduced quality of life. Retrospective studies show a higher incidence of delirium in patients with seizures. However, these studies do not systematically detect subclinical seizures, so the incidence of seizures after cardiac surgery remains speculative. The objective of this study is to determine the prevalence of electrographic seizures after elective open-chamber cardiac surgery. METHODS This prospective, blinded, monocentric, observational study investigated patients scheduled for elective open-chamber valve reconstruction or replacement. Anaesthesia, surgery and postoperative treatment were standardized and not influenced by the presented observation. After surgery, all patients arrived at the ICU, and EEG monitoring started within the first hour. EEG recording was continuously performed for up to 24 h, and the results were independently analysed by two blinded EEG board-certified neurologists. RESULTS 100 patients were included. Abnormal EEG patterns were present in 33% of patients, and 9% of all patients showed electrographic seizures. The main EEG activity at the beginning of each recording was suppressed or showed a burst-suppression pattern, and at the end of recording, all patients had an alpha/theta rhythm. An association between electrographic seizures and delirium was found (pχ2 < 0.01). CONCLUSION This study reveals a surprisingly high incidence of abnormal EEG patterns and electrographic seizures in patients undergoing open-chamber cardiac surgery. As electrographic seizures are associated with the incidence of delirium, this finding is a relevant phenomenon in the post-cardiac surgery ICU population.
DDC: 610 Medizin
610 Medical sciences
Institution: Johannes Gutenberg-Universität Mainz
Department: FB 04 Medizin
Place: Mainz
ROR: https://ror.org/023b0x485
DOI: http://doi.org/10.25358/openscience-5764
Version: Published version
Publication type: Zeitschriftenaufsatz
License: CC BY-NC
Information on rights of use: https://creativecommons.org/licenses/by-nc/4.0/
Journal: Intensive care medicine
46
Pages or article number: 1418
1424
Publisher: Springer
Publisher place: Berlin u.a.
Issue date: 2020
ISSN: 1432-1238
Publisher URL: https://doi.org/10.1007/s00134-020-06073-8
Publisher DOI: 10.1007/s00134-020-06073-8
Appears in collections:JGU-Publikationen

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