Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-21Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Bayer, Franziska | - |
| dc.contributor.author | Ascher, Stefanie | - |
| dc.contributor.author | Potarollo, Giulia | - |
| dc.contributor.author | Reinhardt, Christoph | - |
| dc.date.accessioned | 2020-01-24T14:12:59Z | - |
| dc.date.available | 2020-01-24T15:12:59Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/23 | - |
| dc.description.abstract | The gut microbiota influence host vascular physiology locally in the intestine, but also evoke remote effects that impact distant organ functions. Amongst others, the microbiota affect intestinal vascular remodeling, lymphatic development, cardiac output and vascular function, myelopoiesis, prothrombotic platelet function, and immunovigilance of the host. Experimentally, host-microbiota interactions are investigated by working with animals devoid of symbiotic bacteria, i.e., by the decimation of gut commensals by antibiotic administration, or by taking advantage of germ-free mouse isolator technology. Remarkably, some of the vascular effects that were unraveled following antibiotic treatment were not observed in the germ-free animal models and vice versa. In this review, we will dissect the manifold influences that antibiotics have on the cardiovascular system and their effects on thromboinflammation. | en_GB |
| dc.description.sponsorship | DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin | - |
| dc.language.iso | eng | - |
| dc.rights | CC BY | de_DE |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
| dc.subject.ddc | 610 Medizin | de_DE |
| dc.subject.ddc | 610 Medical sciences | en_GB |
| dc.title | Antibiotic treatment protocols and germ-free mouse models in vascular research | en_GB |
| dc.type | Zeitschriftenaufsatz | de_DE |
| dc.identifier.urn | urn:nbn:de:hebis:77-publ-595205 | - |
| dc.identifier.doi | http://doi.org/10.25358/openscience-21 | - |
| jgu.type.dinitype | article | - |
| jgu.type.version | Published version | en_GB |
| jgu.type.resource | Text | - |
| jgu.organisation.department | FB 04 Medizin | - |
| jgu.organisation.department | Externe Einrichtungen | - |
| jgu.organisation.number | 0000 | - |
| jgu.organisation.number | 2700 | - |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
| jgu.rights.accessrights | openAccess | - |
| jgu.journal.title | Frontiers in immunology | - |
| jgu.journal.volume | 10 | - |
| jgu.pages.alternative | Art. 2174 | - |
| jgu.publisher.year | 2019 | - |
| jgu.publisher.name | Frontiers Media | - |
| jgu.publisher.place | Lausanne | - |
| jgu.publisher.uri | http://dx.doi.org/10.3389/fimmu.2019.02174 | - |
| jgu.publisher.issn | 1664-3224 | - |
| jgu.organisation.place | Mainz | - |
| jgu.subject.ddccode | 610 | - |
| opus.date.accessioned | 2020-01-24T14:12:59Z | - |
| opus.date.modified | 2020-02-06T10:34:00Z | - |
| opus.date.available | 2020-01-24T15:12:59 | - |
| opus.subject.dfgcode | 00-000 | - |
| opus.organisation.string | FB 04: Medizin: Centrum für Thrombose und Hämostase (CTH) | de_DE |
| opus.identifier.opusid | 59520 | - |
| opus.institute.number | 0463 | - |
| opus.institute.number | 9999 | - |
| opus.metadataonly | false | - |
| opus.type.contenttype | Keine | de_DE |
| opus.type.contenttype | None | en_GB |
| opus.affiliated | Reinhardt, Christoph | - |
| jgu.publisher.doi | 10.3389/fimmu.2019.02174 | |
| jgu.organisation.ror | https://ror.org/023b0x485 | |
| Appears in collections: | JGU-Publikationen | |
