Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-10087
Authors: | Staubitz-Vernazza, Julia I. Schwind, Sina Lozan, Oana Musholt, Thomas J. |
Title: | A 16-year single-center series of trachea resections for locally advanced thyroid carcinoma |
Online publication date: | 20-Feb-2024 |
Year of first publication: | 2024 |
Language: | english |
Abstract: | (1) Background: Infiltration of the aerodigestive tract in advanced thyroid carcinoma determines the prognosis and quality of life. Different stages of tracheal tumor invasion require customization of the surgical concept. (2) Methods: In the period from January 2007 to January 2023, patients who underwent surgery for advanced thyroid carcinomas with trachea resections were included in a retrospective observational study. The surgical resection concepts and operation-associated complications were documented. The overall survival and post-resection survival were analyzed. (3) Results: From 2007 to 2023, at the single-center UMC Mainz, 33 patients (15 female and 18 male) underwent neck surgery with trachea resections for locally advanced thyroid carcinomas. Of these, 14 were treated with non-transmural (trachea shaving) and 19 transmural trachea resections (9 “window” resections, 6 near-circular resections, 3 sleeve resections and 1 total laryngectomy with extramucosal esophageal resection). The two-year postoperative survival rate was 82.0 percent. The two-year recurrence-free survival rate was 75.0 percent (mean follow-up period: 29.2 months). (4) Conclusions: Tracheal resections for locally advanced tumor infiltration are feasible as an element of highly individualized treatment concepts. |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-10087 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
Document type specification: | Scientific article |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | Cancers 16 1 |
Pages or article number: | 163 |
Publisher: | MDPI |
Publisher place: | Basel |
Issue date: | 2024 |
ISSN: | 2072-6694 |
Publisher DOI: | 10.3390/cancers16010163 |
Appears in collections: | DFG-491381577-G |
Files in This Item:
File | Description | Size | Format | ||
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a_16year_singlecenter_series_-20240214145726375.pdf | 2.26 MB | Adobe PDF | View/Open |