Authors:	Halfmann, Moritz C. Luetkens, Julian A. Langenbach, Isabel L. Kravchenko, Dmitrij Wenzel, Philip Emrich, Tilman Isaak, Alexander
Title:	Cardiac MRI findings in patients clinically referred for evaluation of post-acute sequelae of SARS-CoV-2 infection
Online publication date:	13-Feb-2024
Year of first publication:	2023
Language:	english
Abstract:	Persistent or recurrent cardiovascular symptoms have been identified as one of the hallmarks of long-COVID or post-acute sequelae of SARS-CoV-2 infection (PASC). The purpose of this study was to determine the prevalence and extent of cardiac abnormalities in patients referred for cardiac MRI due to clinical evidence of PASC. To investigate this, two tertiary care hospitals identified all patients who were referred for cardiac MRI under the suspicion of PASC in a 2-year period and retrospectively included them in this study. Patients with previously known cardiac diseases were excluded. This resulted in a total cohort of 129 patients (63, 51% female; age 41 ± 16 years). The majority of patients (57%) showed normal cardiac results. No patient had active myocarditis or an acute myocardial infarction. However, 30% of patients had evidence of non-ischemic myocardial fibrosis, which exceeds the prevalence in the normal adult population and suggests that a possible history of myocarditis might explain persistent symptoms in the PASC setting.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-10000
Version:	Published version
Publication type:	Zeitschriftenaufsatz
Document type specification:	Scientific article
License:	CC BY
Information on rights of use:	https://creativecommons.org/licenses/by/4.0/
Journal:	Diagnostics 13 13
Pages or article number:	2172
Publisher:	MDPI
Publisher place:	Basel
Issue date:	2023
ISSN:	2075-4418
Publisher DOI:	10.3390/diagnostics13132172
Appears in collections:	DFG-491381577-G