PHES scores have limited impact on the risk of overt HE in patients with minimal HE
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Abstract
Background:
Minimal hepatic encephalopathy, defined by the portosystemic hepatic encephalopathy score (PHES), is associated with a higher risk of subsequent OHE. It remains unclear if there is a stepwise increase in OHE risk with worse PHES results.
Methods:
In this multicenter study, patients with minimal hepatic encephalopathy, as defined by abnormal PHES, were followed for OHE development.
Results:
In all, 207 patients were included. There was no stepwise increase in OHE risk with worse PHES results.
Conclusions:
Abnormal PHES is associated with a higher OHE risk, but we found no stepwise increase in OHE risk with worse PHES results below the established cutoff.
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Hepatology communications, 8, 5, Wolters Kluwer Health, Alphen aan den Rijn, 2024, https://doi.org/10.1097/HC9.0000000000000438