Awake tracheal intubation in routine airway management : a retrospective analysis in a tertiary centre

dc.contributor.authorPirlich, Nina
dc.contributor.authorBerk, Alexander
dc.contributor.authorHummer, Regina
dc.contributor.authorSchmidtmann, Irene
dc.contributor.authorEpp, Katharina
dc.contributor.authorKriege, Marc
dc.contributor.authorWittenmeier, Eva
dc.date.accessioned2025-07-30T09:48:33Z
dc.date.available2025-07-30T09:48:33Z
dc.date.issued2024
dc.description.abstractIntroduction While awake tracheal intubation (ATI) is regarded as the gold standard for difficult airway management according to current guidelines, there seems to be a reluctance in its application. This retrospective cohort study, conducted at a German tertiary hospital over a 2-year period, aimed to demonstrate that integrating awake tracheal intubation using flexible bronchoscopy (ATI:FB) into routine airway management makes it a successful and safe approach. Materials and methods In 2019 and 2020, records from the data acquisition system (DAQ) and archived anesthesia records were screened to evaluate the specifics of ATI:FB procedures, focusing on overall success and safety. Analysis included complications, time required for ATI:FB, and potential influencing factors such as patient characteristics, indication, medical/operative specialty, sedation technique, route and experience of anesthesiologist. Logistic regression assessed the impact of various variables on occurrence of complications and linear regression, with log(time) as the dependent variable, evaluated median time required to perform ATI:FB. Results ATI:FB constituted 4.3 % (n = 1,911) of all airway management procedures, predominantly observed in dental, oral, and maxillofacial surgery (46.5 %) and otorhinolaryngology (38.4 %). The success rate for ATI:FB was notably high at 99.6 %, with only 5.4 % of cases experiencing complications, including technical issues, agitation, and visibility obstruction due to mucous secretion. Complication risk was influenced by the medical specialty and the experience of the anesthesiologist. A strong effect was observed in otorhinolaryngology (OR = 4.54, 95 % CI [1.64; 14.06]). The median time required for ATI:FB was 16 minutes (IQR: 11 to 23), with factors such as indication (p < 0.0001), experience of anesthesiologist (p < 0.0001), sedation technique (p = 0.0408), priority of the procedure (p = 0.0134), and medical/operative specialty (p < 0.0001) affecting the duration. The median time required for ATI:FB differed significantly based on the experience of the anesthesiologist (p < 0.0001). Conclusion ATI:FB proves successful and safe, with low complications and manageable procedural time. Experience of the anesthesiologist is a modifiable factor enhancing safety, emphasizing the need for ATI:FB integration into routine airway management.en
dc.identifier.doihttps://doi.org/10.25358/openscience-12854
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/12875
dc.language.isoeng
dc.rightsCC-BY-4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610 Medizinde
dc.subject.ddc610 Medical sciencesen
dc.titleAwake tracheal intubation in routine airway management : a retrospective analysis in a tertiary centreen
dc.typeZeitschriftenaufsatz
jgu.journal.issue3
jgu.journal.titlePLOS ONE
jgu.journal.volume19
jgu.organisation.departmentFB 04 Medizin
jgu.organisation.nameJohannes Gutenberg-Universität Mainz
jgu.organisation.number2700
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.alternativee0299071
jgu.publisher.doi10.1371/journal.pone.0299071
jgu.publisher.eissn1932-6203
jgu.publisher.namePLOS
jgu.publisher.placeSan Francisco, California, US
jgu.publisher.year2024
jgu.rights.accessrightsopenAccess
jgu.subject.ddccode610
jgu.subject.dfgLebenswissenschaften
jgu.type.dinitypeArticleen_GB
jgu.type.resourceText
jgu.type.versionPublished version

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