Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo

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dc.contributor.authorRiemenschneider, Henrick
dc.contributor.authorSimonetti, Francesca
dc.contributor.authorSheth, Udit
dc.contributor.authorKatona, Eszter
dc.contributor.authorRoth, Stefan
dc.contributor.authorHutten, Saskia
dc.contributor.authorFarny, Daniel
dc.contributor.authorMichaelsen, Meike
dc.contributor.authorNuscher, Brigitte
dc.contributor.authorSchmidt, Michael K.
dc.contributor.authorFlatley, Andrew
dc.contributor.authorSchepers, Aloys
dc.contributor.authorGruijs da Silva, Lara A.
dc.contributor.authorZhou, Qihui
dc.contributor.authorKlopstock, Thomas
dc.contributor.authorLiesz, Arthur
dc.contributor.authorArzberger, Thomas
dc.contributor.authorHerms, Jochen
dc.contributor.authorFeederle, Regina
dc.contributor.authorGendron, Tania F.
dc.contributor.authorDormann, Dorothee
dc.contributor.authorEdbauer, Dieter
dc.date.accessioned2024-04-02T07:10:10Z
dc.date.available2024-04-02T07:10:10Z
dc.date.issued2023
dc.date.updated2024-03-31T16:23:48Z
dc.identifier.doihttp://doi.org/10.25358/openscience-10254
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/10272
dc.language.isoeng
dc.rightsCC-BY-4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc570 Biowissenschaftende_DE
dc.subject.ddc570 Life sciencesen_GB
dc.titleTargeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivoen_GB
dc.typeZeitschriftenaufsatzde_DE
elements.object.id170796
elements.object.labelsNeurodegeneration
elements.object.labelsAmyotrophic lateral sclerosis
elements.object.labelsFrontotemporal dementia
elements.object.labelsTDP-43
elements.object.labelsImmunotherapy
elements.object.labelsPhase separation
elements.object.labelsAggregation
elements.object.labelsIntermediate Filaments
elements.object.labelsAnimals
elements.object.labelsMice
elements.object.labelsNF-kappa B
elements.object.labelsAntibodies, Monoclonal
elements.object.labelsEpitopes
elements.object.labelsImmunization
elements.object.labelsAggregation
elements.object.labelsAmyotrophic lateral sclerosis
elements.object.labelsFrontotemporal dementia
elements.object.labelsImmunotherapy
elements.object.labelsNeurodegeneration
elements.object.labelsPhase separation
elements.object.labelsTDP-43
elements.object.labelsAnimals
elements.object.labelsMice
elements.object.labelsAntibodies, Monoclonal
elements.object.labelsEpitopes
elements.object.labelsImmunization
elements.object.labelsIntermediate Filaments
elements.object.labelsNF-kappa B
elements.object.labels0601 Biochemistry and Cell Biology
elements.object.labels1103 Clinical Sciences
elements.object.labels1109 Neurosciences
elements.object.labels3101 Biochemistry and cell biology
elements.object.labels3209 Neurosciences
elements.object.typejournal-article
jgu.journal.titleActa Neuropathologica Communications
jgu.journal.volume11
jgu.organisation.departmentFB 10 Biologiede_DE
jgu.organisation.nameJohannes Gutenberg-Universität Mainzde_DE
jgu.organisation.number7970
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.alternative112
jgu.publisher.doi10.1186/s40478-023-01592-z
jgu.publisher.issn2051-5960
jgu.publisher.licenceCC BY
jgu.publisher.nameBioMed Central
jgu.publisher.placeLondon
jgu.publisher.year2023
jgu.rights.accessrightsopenAccessen_GB
jgu.subject.ddccode570
jgu.type.dinitypeArticleen_GB
jgu.type.resourceTexten_GB
jgu.type.versionPublished versionen_GB

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