Absolute optical chiral analysis using cavity-enhanced polarimetry

Bougas, Lykourgos; Byron, Joseph; Budker, Dmitry; Williams, Jonathan

Absolute optical chiral analysis using cavity-enhanced polarimetry

dc.contributor.author	Bougas, Lykourgos
dc.contributor.author	Byron, Joseph
dc.contributor.author	Budker, Dmitry
dc.contributor.author	Williams, Jonathan
dc.date.accessioned	2024-02-06T15:39:14Z
dc.date.available	2024-02-06T15:39:14Z
dc.date.issued	2022
dc.date.updated	2023-10-17T18:57:23Z
dc.description.abstract	Chiral analysis is central for scientific advancement in the fields of chemistry, biology, and medicine. It is also indispensable in the development and quality control of chiral compounds in the chemical and pharmaceutical industries. Here, we present the concept of absolute optical chiral analysis, as enabled by cavity-enhanced polarimetry, which allows for accurate unambiguous enantiomeric characterization and enantiomeric excess determination of chiral compounds within complex mixtures at trace levels, without the need for calibration, even in the gas phase. Our approach and technology enable the absolute postchromatographic chiral analysis of complex gaseous mixtures, the rapid quality control of complex mixtures containing chiral volatile compounds, and the online in situ observation of chiral volatile emissions from a plant under stress.	en_GB
dc.identifier.doi	http://doi.org/10.25358/openscience-10059
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/10077
dc.language.iso	eng	de
dc.rights	CC-BY-NC-4.0	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject.ddc	530 Physik	de_DE
dc.subject.ddc	530 Physics	en_GB
dc.title	Absolute optical chiral analysis using cavity-enhanced polarimetry	en_GB
dc.type	Zeitschriftenaufsatz	de
elements.object.id	163926
elements.object.type	journal-article
jgu.journal.issue	22	de
jgu.journal.title	Science advances	de
jgu.journal.volume	8	de
jgu.organisation.department	FB 08 Physik, Mathematik u. Informatik	de
jgu.organisation.department	Helmholtz Institut Mainz	de
jgu.organisation.name	Johannes Gutenberg-Universität Mainz
jgu.organisation.number	7940
jgu.organisation.number	9050
jgu.organisation.place	Mainz
jgu.organisation.ror	https://ror.org/023b0x485
jgu.pages.alternative	eabm3749	de
jgu.publisher.doi	10.1126/sciadv.abm3749	de
jgu.publisher.issn	2375-2548	de
jgu.publisher.licence	CC BY-NC
jgu.publisher.name	American Association for the Advancement of Science	de
jgu.publisher.place	Washington, DC u.a.	de
jgu.publisher.year	2022
jgu.rights.accessrights	openAccess
jgu.subject.ddccode	530	de
jgu.subject.dfg	Naturwissenschaften	de
jgu.type.contenttype	Scientific article	de
jgu.type.dinitype	Article	en_GB
jgu.type.resource	Text	de
jgu.type.version	Published version	de

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