Glucose as an eco-friendly reductant in a one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones

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dc.contributor.authorSantos, Thiago dos
dc.contributor.authorGrundke, Caroline
dc.contributor.authorLucas, Tobias
dc.contributor.authorGroßmann, Luca
dc.contributor.authorClosoki, Giuliano Cesar
dc.contributor.authorOpatz, Till
dc.date.accessioned2021-07-06T07:38:19Z
dc.date.available2021-07-06T07:38:19Z
dc.date.issued2020
dc.description.abstractCarbohydrates such as glucose are an abundant renewable resource that can be employed in synthetic processes as a source of carbon and/or hydrogen to yield products of high economical and biological impact. Herein, we report a versatile and environmentally friendly protocol for the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones, a privileged scaffold in medicinal chemistry, based on the use of glucose as an eco-friendly reductant in alkaline aqueous medium. This method can be viewed as a blueprint for the development of further one-pot sequences involving glucose as a reductant.en_GB
dc.identifier.doihttp://doi.org/10.25358/openscience-6174
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/6183
dc.language.isoengde
dc.rightsCC-BY-NC-ND-4.0*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.ddc540 Chemiede_DE
dc.subject.ddc540 Chemistry and allied sciencesen_GB
dc.titleGlucose as an eco-friendly reductant in a one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-onesen_GB
dc.typeZeitschriftenaufsatzde
jgu.journal.issue41de
jgu.journal.titleEuropean journal of organic chemistryde
jgu.journal.volume2020de
jgu.organisation.departmentFB 09 Chemie, Pharmazie u. Geowissensch.de
jgu.organisation.nameJohannes Gutenberg-Universität Mainz
jgu.organisation.number7950
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.end6432de
jgu.pages.start6429de
jgu.publisher.doi10.1002/ejoc.202000970
jgu.publisher.issn1099-0690de
jgu.publisher.nameWiley-VCHde
jgu.publisher.placeWeinheimde
jgu.publisher.urihttps://doi.org/10.1002/ejoc.202000970de
jgu.publisher.year2020
jgu.rights.accessrightsopenAccess
jgu.subject.ddccode540de
jgu.type.dinitypeArticleen_GB
jgu.type.resourceTextde
jgu.type.versionPublished versionde

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