Survey of physicians and healers using amygdalin to treat cancer patients

dc.contributor.authorMarkowitsch, Sascha D.
dc.contributor.authorBinali, Sali
dc.contributor.authorRutz, Jochen
dc.contributor.authorChun, Felix K.-H.
dc.contributor.authorHaferkamp, Axel
dc.contributor.authorTsaur, Igor
dc.contributor.authorJuengel, Eva
dc.contributor.authorFischer, Nikita D.
dc.contributor.authorThomas, Anita
dc.contributor.authorBlaheta, Roman A.
dc.date.accessioned2025-08-05T08:28:28Z
dc.date.available2025-08-05T08:28:28Z
dc.date.issued2024
dc.description.abstractAmygdalin is purported to exhibit anti-cancer properties when hydrolyzed to hydrogen cyanide (HCN). However, knowledge about amygdalin efficacy is limited. A questionnaire evaluating the efficacy, treatment, and dosing protocols, reasons for use, HCN levels, and toxicity was distributed to physicians and healers in Germany, providing amygdalin as an anti-cancer drug. Physicians (20) and healers (18) provided amygdalin over 8 (average) years to nearly 80 annually treated patients/providers. Information about amygdalin was predominantly obtained from colleagues (55%). Amygdalin was administered both intravenously (100%) and orally (32%). Intravenous application was considered to maximally delay disease progression (90%) and relieve symptoms (55%). Dosing was based on recommendations from colleagues (71%) or personal experience (47%). If limited success became apparent after an initial 3g/infusion, infusions were increased to 27g/infusion. Treatment response was primarily monitored with established (26%) and non-established tumor markers (19%). 90% did not monitor HCN levels. Negative effects were restricted to a few dizzy spells and nausea. Only 58% were willing to participate in clinical trials or contribute data for analysis (34%). Amygdalin infusions are commonly administered by healers and physicians with few side effects. The absence of standardized treatment calls for guidelines. Since intravenous application bypasses metabolization, re-evaluation of its mode of action is required.en_US
dc.identifier.doihttps://doi.org/10.25358/openscience-12975
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/12996
dc.language.isoeng
dc.rightsCC-BY-4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610 Medizinde
dc.subject.ddc610 Medical sciencesen
dc.titleSurvey of physicians and healers using amygdalin to treat cancer patientsen_US
dc.typeZeitschriftenaufsatz
jgu.journal.issue13
jgu.journal.titleNutrients
jgu.journal.volume16
jgu.organisation.departmentFB 04 Medizin
jgu.organisation.nameJohannes Gutenberg-Universität Mainz
jgu.organisation.number2700
jgu.organisation.placeMainz
jgu.organisation.rorhttps://ror.org/023b0x485
jgu.pages.alternative2068
jgu.publisher.doi10.3390/nu16132068
jgu.publisher.eissn2072-6643
jgu.publisher.nameMDPI
jgu.publisher.placeBasel
jgu.publisher.year2024
jgu.rights.accessrightsopenAccess
jgu.subject.ddccode610
jgu.subject.dfgLebenswissenschaften
jgu.type.contenttypeScientific article
jgu.type.dinitypeArticleen_GB
jgu.type.resourceText
jgu.type.versionPublished version

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