A rare case of primary signet ring cell carcinoma of the urinary bladder in a young woman

Abstract

Primary signet ring cell carcinoma of the urinary bladder (PSRCCB) is an exceedingly rare subtype of urinary bladder carcinoma, comprising 0.12%–0.6% of cases, with a poor prognosis. This case report details a distinctive case of a 32-year-old woman with PSRCCB, presenting without typical risk factors and posing diagnostic and therapeutic challenges. Initial symptoms included urinary tract infection and lower abdominal pain. Imaging and histological assessments identified a mucinous adenocarcinoma with signet ring cell components. The patient underwent curative open partial cystectomy, given her young age and localized tumor, avoiding lymphadenectomy and adjuvant chemotherapy due to complete tumor resection and absence of metastases. Postoperative follow-up showed no pathological findings, underscoring the importance of individualized treatment strategies in rare cancer cases. This case contributes to the limited data on PSRCCB and its management.