Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders
| dc.contributor.author | Poggi, Giulia | |
| dc.contributor.author | Treccani, Giulia | |
| dc.contributor.author | Bey, Martina von der | |
| dc.contributor.author | Tanti, Arnaud | |
| dc.contributor.author | Schmeisser, Michael J. | |
| dc.contributor.author | Müller, Marianne | |
| dc.date.accessioned | 2025-10-09T09:01:26Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Psychiatric research has shifted from a neuroncentric view to understanding mental disorders as disturbances of heterogeneous brain networks. Oligodendrocyte precursor cells (OPCs)— actively involved in the modulation of neuronal functions – are altered in psychiatric patients, but the extent and related consequences are unclear. This review explores canonical and non-canonical OPC-related pathways in schizophrenia, bipolar disorder, post-traumatic stress disorder, and depression in humans, highlighting potential mechanisms shared across diagnostic entities. | en |
| dc.identifier.doi | https://doi.org/10.25358/openscience-13462 | |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/13483 | |
| dc.language.iso | eng | |
| dc.rights | CC-BY-4.0 | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject.ddc | 610 Medizin | de |
| dc.subject.ddc | 610 Medical sciences | en |
| dc.title | Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders | en |
| dc.type | Zeitschriftenaufsatz | |
| jgu.identifier.uuid | 6318c9df-a83e-4739-8734-d64f22d15d5c | |
| jgu.journal.title | npj mental health research | |
| jgu.journal.volume | 4 | |
| jgu.organisation.department | FB 04 Medizin | |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | |
| jgu.organisation.number | 2700 | |
| jgu.organisation.place | Mainz | |
| jgu.organisation.ror | https://ror.org/023b0x485 | |
| jgu.pages.alternative | 19 | |
| jgu.publisher.doi | 10.1038/s44184-025-00133-x | |
| jgu.publisher.eissn | 2731-4251 | |
| jgu.publisher.name | Nature | |
| jgu.publisher.place | London | |
| jgu.publisher.year | 2025 | |
| jgu.rights.accessrights | openAccess | |
| jgu.subject.ddccode | 610 | |
| jgu.subject.dfg | Lebenswissenschaften | |
| jgu.type.dinitype | Article | en_GB |
| jgu.type.resource | Text | |
| jgu.type.version | Published version |