A short route to midazolam via Michael addition to a nitroolefin
| dc.contributor.author | Brunotte, Lara | |
| dc.contributor.author | Donsbach, Kai Oliver | |
| dc.date.accessioned | 2025-12-02T10:48:49Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | A new approach to midazolam through Michael addition of 2-aminobenzophenone with a nitroolefin as a key step is reported. We devised a telescoped four-step synthesis using only one single protecting group, resulting in an excellent atom economy. | en |
| dc.identifier.doi | https://doi.org/10.25358/openscience-13760 | |
| dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/13781 | |
| dc.language.iso | eng | |
| dc.rights | CC-BY-4.0 | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject.ddc | 540 Chemie | de |
| dc.subject.ddc | 540 Chemistry and allied sciences | en |
| dc.title | A short route to midazolam via Michael addition to a nitroolefin | en |
| dc.type | Zeitschriftenaufsatz | |
| jgu.identifier.uuid | 583f5b34-3a5f-49e1-a746-b15f0e9adf6c | |
| jgu.journal.issue | 11 | |
| jgu.journal.title | Organic process research & development | |
| jgu.journal.volume | 29 | |
| jgu.organisation.department | FB 09 Chemie, Pharmazie u. Geowissensch. | |
| jgu.organisation.name | Johannes Gutenberg-Universität Mainz | |
| jgu.organisation.number | 7950 | |
| jgu.organisation.place | Mainz | |
| jgu.organisation.ror | https://ror.org/023b0x485 | |
| jgu.pages.end | 2962 | |
| jgu.pages.start | 2955 | |
| jgu.publisher.doi | 10.1021/acs.oprd.5c00320 | |
| jgu.publisher.eissn | 1520-586X | |
| jgu.publisher.name | American Chemical Society | |
| jgu.publisher.place | Washington, DC | |
| jgu.publisher.year | 2025 | |
| jgu.rights.accessrights | openAccess | |
| jgu.subject.ddccode | 540 | |
| jgu.subject.dfg | Naturwissenschaften | |
| jgu.type.dinitype | Article | en_GB |
| jgu.type.resource | Text | |
| jgu.type.version | Published version |