Authors:	Farmakis, Ioannis T. Kaier, Klaus Hobohm, Lukas Mohr, Katharina Valerio, Luca Barco, Stefano Konstantinides, Stavros V. Binder, Harald
Title:	Healthcare resource utilisation and associated costs after low-risk pulmonary embolism : pre-specified analysis of the Home Treatment of Pulmonary Embolism (HoT-PE) study
Online publication date:	23-Jan-2024
Year of first publication:	2024
Language:	english
Abstract:	Background Pulmonary embolism (PE) and its sequelae impact healthcare systems globally. Low-risk PE patients can be managed with early discharge strategies leading to cost savings, but post-discharge costs are undetermined. Purpose To define healthcare resource utilisation and overall costs during follow-up of low-risk PE. Methods We used an incidence-based, bottom–up approach and calculated direct and indirect costs over 3-month follow-up after low-risk PE, with data from the Home Treatment of Patients with Low-Risk Pulmonary Embolism (HoT-PE) cohort study. Results Average 3-month costs per patient having suffered low-risk PE were 7029.62 €; of this amount, 4872.93 € were associated with PE, accounting to 69.3% of total costs. Specifically, direct costs totalled 3019.33 €, and of those, 862.64 € (28.6%) were associated with PE. Anticoagulation (279.00 €), rehospitalisations (296.83 €), and ambulatory visits (194.95 €) comprised the majority of the 3-month direct costs. The remaining costs amounting to 4010.29 € were indirect costs due to loss of productivity. Conclusion In a patient cohort with acute low-risk PE followed over 3 months, the majority of costs were indirect costs related to productivity loss, whereas direct, PE-specific post-discharge costs were low. Effective interventions are needed to reduce the burden of PE and associated costs, especially those related to productivity loss.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-9955
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY
Information on rights of use:	https://creativecommons.org/licenses/by/4.0/
Journal:	Clinical research in cardiology Version of Record (VoR)
Publisher:	Springer
Publisher place:	Berlin
Issue date:	2024
ISSN:	1861-0692
Publisher DOI:	10.1007/s00392-023-02355-5
Appears in collections:	DFG-491381577-H