Authors:	Koch, Martina Kraus, Daniel Boedecker-Lips, Simone Mittler, Jens Tieken, Ineke Weinmann-Menke, Julia
Title:	Successful transplantation of four kidney grafts from two small pediatric donors with anuric acute renal failure into adult recipients
Online publication date:	12-Sep-2023
Year of first publication:	2023
Language:	english
Abstract:	Background Kidneys from infants with anuric acute kidney injury (AKI) only rarely get accepted for transplantation despite encouraging data that such kidneys can have very good long-term outcome. Methods We report the transplantation of four kidney grafts from two pediatric donors (3 and 4 years) with anuric acute kidney injury as single kidneys into four adult recipients. Results All grafts gained function within 14 days posttransplantation, only one recipient needed dialysis after transplantation. None of the recipients suffered from surgical complications. One month after transplantation, all recipients were free of dialysis. Estimated glomerular filtration rates (eGFR) 3 months after transplantation were 37, 40, 50, and 83 mL/min/1.73 m2. eGFR increased further through month 6, reaching 45, 50, 58, and 89 mL/min/1.73 m2. Conclusion These cases highlight the feasibility of successful transplantation of single pediatric kidney grafts into adult recipients despite anuric AKI of the donor.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-9527
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nc-nd/4.0/
Journal:	Pediatric transplantation 27 5
Pages or article number:	e14542
Publisher:	Wiley-Blackwell
Publisher place:	Oxford u.a
Issue date:	2023
ISSN:	1399-3046
Publisher DOI:	10.1111/petr.14542
Appears in collections:	DFG-491381577-H