Authors:	Graafen, Dirk
Title:	Dosis und Bildqualität der Photon-Counting HRCT der Lunge
Online publication date:	10-Mar-2023
Year of first publication:	2023
Language:	english
Abstract:	Purpose: Photon-counting detector computed tomography (PCD-CT) has the potential to significantly improve CT imaging in many ways including, but not limited to, low-dose high-resolution CT (HRCT) of the lung. The aim of this study was to perform an intrapatient com- parison of the radiation dose and image quality of PCD-CT compared with conventional energy-integrating detector CT (EID-CT). Methods: A total of 32 consecutive patients with available PCD-CT and EID-CT HRCT scans were included in the final analysis. The CT dose index (CTDIvol) was extracted from patient dose reports. Qualitative image analysis comprised the lung parenchyma and mediastinal struc- tures and was assessed by 3 readers using a 5-point Likert scale. Quan- titative image analysis included assessment of noise and signal-to-noise ratio in the lung parenchyma, trachea, aorta, muscle, and background. Results: The mean CTDIvol was 2.0 times higher in the conventional EID-CT scans (1.8 ± 0.5 mGy) compared with PCD-CT (0.9±0.5 mGy, P<0.001). The overall image quality was rated significantly better by all 3 raters (P < 0.001) in the PCD-CT relative to the EID-CT. Quantitative analysis showed no significant differ- ences in noise and signal-to-noise ratio in the lung parenchyma between PCD-CT and EID-CT. Conclusion: Compared with conventional EID-CT scans, PCD-CT demonstrated similar or better objective and subjective image quality at significantly reduced dose levels in an intrapatient com- parison. These results and their effect on clinical decision-making should be further investigated in prospective studies.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8880
URN:	urn:nbn:de:hebis:77-openscience-ce64bdb1-3893-4609-b9d7-e2c501ec70eb0
Version:	Original work
Publication type:	Dissertation
License:	In Copyright
Information on rights of use:	http://rightsstatements.org/vocab/InC/1.0/
Extent:	16 Blatt ; Illustrationen, Diagramme
Appears in collections:	JGU-Publikationen