Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-8847
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dc.contributor.authorStoffers-Winterling, Jutta M.-
dc.contributor.authorStorebø, Ole Jakob-
dc.contributor.authorKongerslev, Mickey T.-
dc.contributor.authorFaltinsen, Erlend-
dc.contributor.authorTodorovac, Adan-
dc.contributor.authorJørgensen, Mie Sedoc-
dc.contributor.authorSales, Christian P.-
dc.contributor.authorEdemann Callesen, Henriette-
dc.contributor.authorPereira Ribeiro, Johanne-
dc.contributor.authorVöllm, Birgit A.-
dc.contributor.authorLieb, Klaus-
dc.contributor.authorSimonsen, Erik-
dc.date.accessioned2023-05-03T13:22:16Z-
dc.date.available2023-05-03T13:22:16Z-
dc.date.issued2022-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/8863-
dc.description.abstractBackground: A recently updated Cochrane review supports the efficacy of psychotherapy for borderline personality disorder (BPD). Aims: To evaluate the effects of standalone and add-on psychotherapeutic treatments more concisely. Method: We applied the same methods as the 2020 Cochrane review, but focused on adult samples and comparisons of active treatments and unspecific control conditions. Standalone treatments (i.e. necessarily including individual psychotherapy as either the sole or one of several treatment components) and add-on interventions (i.e. complementing any ongoing individual BPD treatment) were analysed separately. Primary outcomes were BPD severity, self-harm, suicide-related outcomes and psychosocial functioning. Secondary outcomes were remaining BPD diagnostic criteria, depression and attrition. Results: Thirty-one randomised controlled trials totalling 1870 participants were identified. Among standalone treatments, statistically significant effects of low overall certainty were observed for dialectical behaviour therapy (self-harm: standardised mean difference (SMD) −0.54, P = 0.006; psychosocial functioning: SMD −0.51, P = 0.01) and mentalisation-based treatment (self-harm: risk ratio 0.51, P < 0.0007; suicide-related outcomes: risk ratio 0.10, P < 0.0001). For adjunctive interventions, moderate-quality evidence of beneficial effects was observed for DBT skills training (BPD severity: SMD −0.66, P = 0.002; psychosocial functioning: SMD −0.45, P = 0.002), and statistically significant low-certainty evidence was observed for the emotion regulation group (BPD severity: mean difference −8.49, P < 0.00001), manual-assisted cognitive therapy (self-harm: mean difference −3.03, P = 0.03; suicide-related outcomes: SMD −0.96, P = 0.005) and the systems training for emotional predictability and problem-solving (BPD severity: SMD −0.48, P = 0.002). Conclusions: There is reasonable evidence to conclude that psychotherapeutic interventions are helpful for individuals with BPD. Replication studies are needed to enhance the certainty of findings.en_GB
dc.language.isoengde
dc.rightsCC BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.ddc150 Psychologiede_DE
dc.subject.ddc150 Psychologyen_GB
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titlePsychotherapies for borderline personality disorder : a focused systematic review and meta-analysisen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-8847-
jgu.type.contenttypeScientific articlede
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleThe British Journal of Psychiatryde
jgu.journal.volume221de
jgu.journal.issue3de
jgu.pages.start538de
jgu.pages.end552de
jgu.publisher.year2022-
jgu.publisher.nameCambridge University Pressde
jgu.publisher.placeCambridgede
jgu.publisher.issn1472-1465de
jgu.organisation.placeMainz-
jgu.subject.ddccode150de
jgu.subject.ddccode610de
jgu.publisher.doi10.1192/bjp.2021.204de
jgu.organisation.rorhttps://ror.org/023b0x485-
jgu.subject.dfgLebenswissenschaftende
Appears in collections:DFG-491381577-H

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