Authors:	Großmann, Luca Marius Beier, Vera Duttenhofer, Lea Lennartz, Laura Opatz, Till
Title:	An iodide-mediated anodic amide coupling
Online publication date:	27-Jan-2023
Year of first publication:	2022
Language:	english
Abstract:	The ubiquity of amide bonds, present in natural products and common pharmaceuticals renders this functional group one of the most prevalent in organic chemistry. Despite its importance and a wide variety of existing methods for its formation, the latter still can be a challenge for classical activating reagents such as chloridating agents or carbodiimides. As the spent reagents often cannot be recycled, the development of more sustainable methods is highly desirable. Herein, we report an operationally simple and mild indirect electrochemical protocol to effect the condensation of carboxylic acids with amines, forming a wide variety of carboxamides.
DDC:	540 Chemie 540 Chemistry and allied sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 09 Chemie, Pharmazie u. Geowissensch.
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8703
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-ND
Information on rights of use:	https://creativecommons.org/licenses/by-nd/4.0/
Journal:	Chemistry - a European journal 28 54
Pages or article number:	e202201768
Publisher:	Wiley-VCH
Publisher place:	Weinheim
Issue date:	2022
ISSN:	1521-3765
Publisher DOI:	10.1002/chem.202201768
Appears in collections:	DFG-491381577-H