Authors:	Kothari, Rohit Szepietowski, Jacek C. Bagot, Martine Sandhu, Sunmeet Patil, Anant Grabbe, Stephan Goldust, Mohamad
Title:	Mycosis fungoides in pediatric population : comprehensive review on epidemiology, clinical presentation, and management
Online publication date:	24-Jan-2023
Year of first publication:	2022
Language:	english
Abstract:	Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. However, it is rare in pediatric population. Most of the cases of pediatric MF present with hypopigmented patches and/or various other forms, which may often mimic common childhood dermatoses, thereby causing a delay in the diagnosis. There are no established treatment guidelines for pediatric MF. As the progression of childhood MF is extremely rare and it has an indolent course, it is usually diagnosed at an early stage (IA, IB, IIA), and hence phototherapy with a response rate of >80% is a well-established effective treatment in children. However, as recurrences are frequently seen on stopping the therapies, a maintenance regimen and long-term follow-up is equally important. This article reviews the epidemiological factors, clinical presentations, diagnosis, and various treatment modalities used in pediatric MF. We analyzed and compared the data of almost 616 childhood MF cases from various studies undertaken from 1988 to 2021.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8633
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC
Information on rights of use:	https://creativecommons.org/licenses/by-nc/4.0/
Journal:	International journal of dermatology 61 12
Pages or article number:	1458 1466
Publisher:	Wiley-Blackwell
Publisher place:	Oxford u.a.
Issue date:	2022
ISSN:	1365-4632
Publisher DOI:	10.1111/ijd.16098
Appears in collections:	DFG-491381577-H