Authors:	Arora, Gulhima Patil, Anant Hooshanginezhad, Zahra Fritz, Klaus Salavastru, Carmen Kassir, Martin Goldman, Mitchel P. Gold, Michael H. Adatto, Maurice Grabbe, Stephan Goldust, Mohamad
Title:	Cellulite: presentation and management
Online publication date:	23-Jan-2023
Year of first publication:	2022
Language:	english
Abstract:	Background Cellulite is a common dermatological condition with a female preponderance, affecting up to 90% post-pubertal females. It is characterized with dimpling and denting of the skin surface, giving it a Peau d'orange appearance. Once considered to be a benign physiological isolated skin condition of only an esthetic concern, cellulite is now considered a pathological entity with systemic associations and a negative psychological impact on patients. Aims The objective of this article was to discuss etiology, pathophysiology, and treatment of cellulite. Materials and methods Literature was screened to retrieve articles from PubMed/Medline and Google Scholar and related websites. Cross-references from the relevant articles were also considered for review. Review articles, clinical studies, systematic reviews, meta-analysis, and relevant information from selected websites were included. Results Several treatment options from lifestyle modifications and topical cosmetic therapies to energy-based devices have been studied for its treatment. However, treatment remains a challenge despite many new modalities in the armamentarium. Laser and light therapies along with radiofrequency are useful treatment options with good safety profile. Acoustic wave therapy, subcision, and 1440-nm Nd:YAG minimally invasive laser are beneficial in cellulite reduction. Discussion Methodological differences in the trials conducted make it difficult to compare different treatment modalities. Conclusion Overall, treatment needs to be individualized based on the patient characteristics and severity of the condition. A combination of treatments is often required in most patients for reducing cellulite.
DDC:	610 Medizin 610 Medical sciences
Institution:	Johannes Gutenberg-Universität Mainz
Department:	FB 04 Medizin
Place:	Mainz
ROR:	https://ror.org/023b0x485
DOI:	http://doi.org/10.25358/openscience-8626
Version:	Published version
Publication type:	Zeitschriftenaufsatz
License:	CC BY-NC
Information on rights of use:	https://creativecommons.org/licenses/by-nc/4.0/
Journal:	Journal of cosmetic dermatology 21 4
Pages or article number:	1393 1401
Publisher:	Wiley-Blackwell
Publisher place:	Oxford
Issue date:	2022
ISSN:	1473-2165
Publisher DOI:	10.1111/jocd.14815
Appears in collections:	DFG-491381577-H