Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit?
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Abstract
Minoxidil solution is used for the treatment of androgenetic alopecia (AGA). Minoxi dil 5% solution has been shown to have superior efficacy to minoxidil 2% solution,
it is unknown whether concentrations of minoxidil > 5% provide additional clinical
benefit. We performed a review of the literature to examine the evidence on the effi cacy and safety of higher concentrations of minoxidil in AGA. A search of the
PubMed database was performed using the keywords ‘minoxidil’, ‘androgenic alope cia’ and ‘pattern hair loss’. Relevant articles, including clinical trials, other clinical
studies, case series and case reports published in English were considered for review.
In addition, relevant references from the bibliography section of the retrieved articles
were also reviewed.
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Clinical and experimental dermatology, 47, 11, Wiley-Blackwell, Oxford u.a., 2022, https://doi.org/10.1111/ced.15338