Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-8026
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Brauer, Jan | - |
dc.contributor.author | Quraishi, Elisabeth | - |
dc.contributor.author | Kammer, Lisa Marie | - |
dc.contributor.author | Opatz, Till | - |
dc.date.accessioned | 2022-10-24T10:28:02Z | - |
dc.date.available | 2022-10-24T10:28:02Z | - |
dc.date.issued | 2021 | - |
dc.identifier.uri | https://openscience.ub.uni-mainz.de/handle/20.500.12030/8041 | - |
dc.description.abstract | A simple visible light photochemical, nickel-catalyzed synthesis of ketones from carboxylic acid-derived precursors is presented. Hantzsch ester (HE) functions as a cheap, green and strong photoreductant to facilitate radical generation and also engages in the Ni-catalytic cycle to restore the reactive species. With this dual role, HE allows for the coupling of a large variety of radicals (1°,2°, benzylic, α-oxy & α-amino) with aroyl and alkanoyl moieties, a new feature in reactions of this type. With both precursors deriving from abundant carboxylic acids, this protocol is a welcome addition to the organic chemistry toolbox. The reaction proceeds under mild conditions without the need for toxic metal reagents or bases and shows a wide scope, including pharmaceuticals and complex molecular architectures. | en_GB |
dc.language.iso | eng | de |
dc.rights | CC BY-NC-ND | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject.ddc | 540 Chemie | de_DE |
dc.subject.ddc | 540 Chemistry and allied sciences | en_GB |
dc.title | Nickel-mediated photoreductive cross coupling of carboxylic acid derivatives for ketone synthesis | en_GB |
dc.type | Zeitschriftenaufsatz | de |
dc.identifier.doi | http://doi.org/10.25358/openscience-8026 | - |
jgu.type.dinitype | article | en_GB |
jgu.type.version | Published version | de |
jgu.type.resource | Text | de |
jgu.organisation.department | FB 09 Chemie, Pharmazie u. Geowissensch. | de |
jgu.organisation.number | 7950 | - |
jgu.organisation.name | Johannes Gutenberg-Universität Mainz | - |
jgu.rights.accessrights | openAccess | - |
jgu.journal.title | Chemistry - a European journal | de |
jgu.journal.volume | 27 | de |
jgu.journal.issue | 72 | de |
jgu.pages.start | 18168 | de |
jgu.pages.end | 18174 | de |
jgu.publisher.year | 2021 | - |
jgu.publisher.name | Wiley-VCH | de |
jgu.publisher.place | Weinheim | de |
jgu.publisher.issn | 1521-3765 | de |
jgu.organisation.place | Mainz | - |
jgu.subject.ddccode | 540 | de |
jgu.publisher.doi | 10.1002/chem.202103486 | de |
jgu.organisation.ror | https://ror.org/023b0x485 | - |
Appears in collections: | JGU-Publikationen |
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![]() | nickelmediated_photoreductive-20221024122840656.pdf | 385.65 kB | Adobe PDF | View/Open |