Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-8010
Authors: Pfirrmann, Daniel
Tug, Suzan
Brosteanu, Oana
Mehdorn, Matthias
Busse, Martin
Grimminger, Peter P.
Lordick, Florian
Glatz, Torben
Hoeppner, Jens
Lang, Hauke
Simon, Perikles
Gockel, Ines
Title: Internet-based perioperative exercise program in patients with Barrett’s carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial
Online publication date: 14-Oct-2022
Year of first publication: 2017
Language: english
Abstract: Background Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence and reduced quality of life. Socioeconomic disadvantages can result from these problems. Physical preconditioning has become a crucial leverage to optimize fitness and lung function in patients scheduled for esophagectomy, in particular during the time period of neoadjuvant therapy. Methods/Study design We designed a prospective multicenter randomized-controlled trial. The objective is to evaluate the impact of an internet-based exercise program on postoperative respiratory parameters and pneumonia rates in patients with Barrett’s carcinoma scheduled for esophagectomy. Patients are randomly assigned to either execute internet-based perioperative exercise program (iPEP), including daily endurance, resistance and ventilation training or treatment as usual (TAU). During neoadjuvant therapy and recovery, patients in the intervention group receive an individually designed intensive exercise program based on functional measurements at baseline. Personal feedback of the supervisor with customized training programs is provided in weekly intervals. Discussion This study will evaluate if an intensive individually adapted training program via online supervision during neoadjuvant therapy will improve cardiorespiratory fitness and reduce pulmonary complications following esophagectomy for Barrett’s cancer.
DDC: 610 Medizin
610 Medical sciences
Institution: Johannes Gutenberg-Universität Mainz
Department: FB 02 Sozialwiss., Medien u. Sport
FB 04 Medizin
Place: Mainz
ROR: https://ror.org/023b0x485
DOI: http://doi.org/10.25358/openscience-8010
Version: Published version
Publication type: Zeitschriftenaufsatz
License: CC BY
Information on rights of use: https://creativecommons.org/licenses/by/4.0/
Journal: BMC cancer
17
1
Pages or article number: Art. 413
Publisher: BioMed Central
Publisher place: London
Issue date: 2017
ISSN: 1471-2407
Publisher URL: http://dx.doi.org/10.1186/s12885-017-3400-8
Publisher DOI: 10.1186/s12885-017-3400-8
Appears in collections:DFG-OA-Publizieren (2012 - 2017)

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