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Authors: Wiltink, Jörg
Michal, Matthias
Wild, Philipp
Schneider, Astrid
König, Jochem
Blettner, Maria
Münzel, Thomas
Schulz, Andreas
Weber, Matthias M.
Fottner, Christian
Pfeiffer, Norbert
Lackner, Karl J.
Beutel, Manfred E.
Title: Associations between depression and diabetes in the community : do symptom dimensions matter? Results from the Gutenberg Health Study
Online publication date: 12-Oct-2022
Year of first publication: 2014
Language: english
Abstract: OBJECTIVES: While a bidirectional relationship between diabetes and depression has been established, there is little knowledge if the associations are due to somatic-affective or cognitive-affective dimensions of depression. RESEARCH DESIGN AND METHODS: In a population-based, representative survey of 15.010 participants we therefore studied the associations of the two dimensions of depression with diabetes and health care utilization among depressed and diabetic participants. Depression was assessed by the Patient Health Questionnaire PHQ-9. RESULTS: We found a linear and consistent association between the intensity of depression and the presence of diabetes increasing from 6.9% in no or minimal depression to 7.6% in mild, 9% in moderate and 10.5% in severe depression. There was a strong positive association between somatic-affective symptoms but not with cognitive-affective symptoms and diabetes. Depression and diabetes were both independently related to somatic health care utilisation. CONCLUSIONS: Diabetes and depression are associated, and the association is primarily driven by the somatic-affective component of depression. The main limitation of our study pertains to the cross-sectional data acquisition. Further longitudinal work on the relationship of obesity and diabetes should differentiate the somatic and the cognitive symptoms of depression.
DDC: 610 Medizin
610 Medical sciences
Institution: Johannes Gutenberg-Universität Mainz
Department: FB 04 Medizin
Place: Mainz
Version: Published version
Publication type: Zeitschriftenaufsatz
License: CC BY
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Journal: PLoS one
Pages or article number: e105499
Publisher: PLoS
Publisher place: Lawrence, Kan.
Issue date: 2014
ISSN: 1932-6203
Publisher URL:
Publisher DOI: 10.1371/journal.pone.0105499
Appears in collections:DFG-OA-Publizieren (2012 - 2017)

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