Gutenberg Open Science: On the origin of BAG(3) and its consequences for an expansion of BAG3's role in protein homeostasis

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-7718

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DC Field	Value	Language
dc.contributor.author	Baeken, Marius W.	-
dc.contributor.author	Behl, Christian	-
dc.date.accessioned	2022-09-12T09:36:28Z	-
dc.date.available	2022-09-12T09:36:28Z	-
dc.date.issued	2022	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/7733	-
dc.description.abstract	The B-cell CLL 2-associated athanogene (BAG) protein family in general and BAG3, in particular, are pivotal elements of cellular protein homeostasis, with BAG3 playing a major role in macroautophagy. In particular, in the contexts of senescence and degeneration, BAG3 has exhibited an essential role often related to its capabilities to organize and remove aggregated proteins. Exciting studies in different species ranging from human, murine, zebrafish, and plant samples have delivered vital insights into BAG3s' (and other BAG proteins') functions and their regulations. However, so far no studies have addressed neither BAG3's evolution nor its phylogenetic position in the BAG family.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY-NC	*
dc.rights.uri	https://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	On the origin of BAG(3) and its consequences for an expansion of BAG3's role in protein homeostasis	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-7718	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Journal of cellular biochemistry	de
jgu.journal.volume	123	de
jgu.journal.issue	1	de
jgu.pages.start	102	de
jgu.pages.end	114	de
jgu.pages.alternative	Special Issue: The co-chaperone BAG3: Orchestrator of the cellular task force in response to stress	de
jgu.publisher.year	2022	-
jgu.publisher.name	Wiley-Liss	de
jgu.publisher.place	New York, NY	de
jgu.publisher.issn	1097-4644	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1002/jcb.29925	de
jgu.organisation.ror	https://ror.org/023b0x485	-
Appears in collections:	JGU-Publikationen

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