Please use this identifier to cite or link to this item:
http://doi.org/10.25358/openscience-7717
Authors: | Schepers, Jana Behl, Christian |
Title: | Lipid droplets and autophagy : links and regulations from yeast to humans |
Online publication date: | 12-Sep-2022 |
Year of first publication: | 2021 |
Language: | english |
Abstract: | Recent advances in the yeast Saccharomyces cerevisiae and higher eukaryotes have been increasingly connecting lipid droplet (LD) dynamics to the regulation of autophagy. In this review we will discuss implications that connect LD de novo synthesis and LD mobilization to autophagy and how autophagy is regulated by these mechanisms. Elucidating these connections might pose a chance to further understand autophagy induction and membrane biogenesis for the growing autophagosome under different conditions. Increasing our understanding of these mechanisms might provide a chance to understand several conditions that might be related to LD dysregulation and, possibly, as a consequence of this, dysregulation of autophagy. |
DDC: | 610 Medizin 610 Medical sciences |
Institution: | Johannes Gutenberg-Universität Mainz |
Department: | FB 04 Medizin |
Place: | Mainz |
ROR: | https://ror.org/023b0x485 |
DOI: | http://doi.org/10.25358/openscience-7717 |
Version: | Published version |
Publication type: | Zeitschriftenaufsatz |
License: | CC BY |
Information on rights of use: | https://creativecommons.org/licenses/by/4.0/ |
Journal: | Journal of cellular biochemistry 122 6 |
Pages or article number: | 602 611 |
Publisher: | Wiley-Liss |
Publisher place: | New York, NY |
Issue date: | 2021 |
ISSN: | 1097-4644 |
Publisher DOI: | 10.1002/jcb.29889 |
Appears in collections: | JGU-Publikationen |
Files in This Item:
File | Description | Size | Format | ||
---|---|---|---|---|---|
lipid_droplets_and_autophagyl-20220905113137662.pdf | 1.44 MB | Adobe PDF | View/Open |