Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6282
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dc.contributor.authorGeyer, Martin-
dc.contributor.authorSotiriou, Efthymios-
dc.contributor.authorKeller, Karsten-
dc.contributor.authorTamm, Alexander R.-
dc.contributor.authorRuf, Tobias F.-
dc.contributor.authorKreidel, Felix-
dc.contributor.authorBeiras-Fernandez, Andres-
dc.contributor.authorKornberger, Angela-
dc.contributor.authorYang, Yang-
dc.contributor.authorEmrich, Tilman-
dc.contributor.authorSchulz, Eberhard-
dc.contributor.authorMünzel, Thomas-
dc.contributor.authorBardeleben, Ralph Stephan von-
dc.date.accessioned2021-08-16T08:28:27Z-
dc.date.available2021-08-16T08:28:27Z-
dc.date.issued2020-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/6292-
dc.description.abstractOBJECTIVES Several interventional approaches have been established for the treatment of severe mitral regurgitation (MR) in patients at elevated risk for surgery. Direct annuloplasty is a relatively novel option in transcatheter mitral valve repair dedicated to reverse pathology in specific subsets of MR. With regard to echocardiographic guidance, this procedure presents with higher efforts in comparison with edge-to-edge therapy to enable safe and exact positioning of the device's anchors; evidence on optimal peri-interventional imaging is sparse. We tested a specific 3D-echo-guidance protocol implementing single-beat multiplanar reconstruction (MPR) and evaluated its feasibility. METHODS Overall, 16 patients consecutively treated with transcatheter direct annuloplasty for severe MR (87.5% functional/6.3% degenerative/6.3% mixed pathology) were entered in this monocentric analysis. Of these, two patients received a combined procedure including edge-to-edge repair. For all implantations, a 3D-echo-guidance protocol inheriting MPR was employed. RESULTS Periprocedural device time decreased continuously (overall mean 140 ± 55.1 minutes, 213 ± 38 minutes in the first 4 vs 108 ± 33 minutes in the last 4 procedures, P = .018) using the MPR-based echo protocol, going along with reduced fluoroscopy times and doses. Technical success rate was high (93.8%) without any serious cardiac-related adverse events. MR could be relevantly improved. CONCLUSION Echocardiographic guidance of transcatheter direct annuloplasty using a real time MPR-based protocol is feasible and safe. Optimized imaging might enable reduced implantation times and potentially increases safety.en_GB
dc.language.isoengde
dc.rightsCC BY*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleFeasibility of a MPR-based 3DTEE guidance protocol for transcatheter direct mitral valve annuloplastyen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-6282-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleEchocardiographyde
jgu.journal.volume37de
jgu.journal.issue9de
jgu.pages.start1436de
jgu.pages.end1442de
jgu.publisher.year2020-
jgu.publisher.nameWiley-Blackwellde
jgu.publisher.placeOxford u.a.de
jgu.publisher.urihttps://doi.org/10.1111/echo.14694de
jgu.publisher.issn1540-8175de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
jgu.publisher.doi10.1111/echo.14694
Appears in collections:JGU-Publikationen

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