Gutenberg Open Science: Feasibility of a MPR-based 3DTEE guidance protocol for transcatheter direct mitral valve annuloplasty

Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6282

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DC Field	Value	Language
dc.contributor.author	Geyer, Martin	-
dc.contributor.author	Sotiriou, Efthymios	-
dc.contributor.author	Keller, Karsten	-
dc.contributor.author	Tamm, Alexander R.	-
dc.contributor.author	Ruf, Tobias F.	-
dc.contributor.author	Kreidel, Felix	-
dc.contributor.author	Beiras-Fernandez, Andres	-
dc.contributor.author	Kornberger, Angela	-
dc.contributor.author	Yang, Yang	-
dc.contributor.author	Emrich, Tilman	-
dc.contributor.author	Schulz, Eberhard	-
dc.contributor.author	Münzel, Thomas	-
dc.contributor.author	Bardeleben, Ralph Stephan von	-
dc.date.accessioned	2021-08-16T08:28:27Z	-
dc.date.available	2021-08-16T08:28:27Z	-
dc.date.issued	2020	-
dc.identifier.uri	https://openscience.ub.uni-mainz.de/handle/20.500.12030/6292	-
dc.description.abstract	OBJECTIVES Several interventional approaches have been established for the treatment of severe mitral regurgitation (MR) in patients at elevated risk for surgery. Direct annuloplasty is a relatively novel option in transcatheter mitral valve repair dedicated to reverse pathology in specific subsets of MR. With regard to echocardiographic guidance, this procedure presents with higher efforts in comparison with edge-to-edge therapy to enable safe and exact positioning of the device's anchors; evidence on optimal peri-interventional imaging is sparse. We tested a specific 3D-echo-guidance protocol implementing single-beat multiplanar reconstruction (MPR) and evaluated its feasibility. METHODS Overall, 16 patients consecutively treated with transcatheter direct annuloplasty for severe MR (87.5% functional/6.3% degenerative/6.3% mixed pathology) were entered in this monocentric analysis. Of these, two patients received a combined procedure including edge-to-edge repair. For all implantations, a 3D-echo-guidance protocol inheriting MPR was employed. RESULTS Periprocedural device time decreased continuously (overall mean 140 ± 55.1 minutes, 213 ± 38 minutes in the first 4 vs 108 ± 33 minutes in the last 4 procedures, P = .018) using the MPR-based echo protocol, going along with reduced fluoroscopy times and doses. Technical success rate was high (93.8%) without any serious cardiac-related adverse events. MR could be relevantly improved. CONCLUSION Echocardiographic guidance of transcatheter direct annuloplasty using a real time MPR-based protocol is feasible and safe. Optimized imaging might enable reduced implantation times and potentially increases safety.	en_GB
dc.language.iso	eng	de
dc.rights	CC BY	*
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	*
dc.subject.ddc	610 Medizin	de_DE
dc.subject.ddc	610 Medical sciences	en_GB
dc.title	Feasibility of a MPR-based 3DTEE guidance protocol for transcatheter direct mitral valve annuloplasty	en_GB
dc.type	Zeitschriftenaufsatz	de
dc.identifier.doi	http://doi.org/10.25358/openscience-6282	-
jgu.type.dinitype	article	en_GB
jgu.type.version	Published version	de
jgu.type.resource	Text	de
jgu.organisation.department	FB 04 Medizin	de
jgu.organisation.number	2700	-
jgu.organisation.name	Johannes Gutenberg-Universität Mainz	-
jgu.rights.accessrights	openAccess	-
jgu.journal.title	Echocardiography	de
jgu.journal.volume	37	de
jgu.journal.issue	9	de
jgu.pages.start	1436	de
jgu.pages.end	1442	de
jgu.publisher.year	2020	-
jgu.publisher.name	Wiley-Blackwell	de
jgu.publisher.place	Oxford u.a.	de
jgu.publisher.uri	https://doi.org/10.1111/echo.14694	de
jgu.publisher.issn	1540-8175	de
jgu.organisation.place	Mainz	-
jgu.subject.ddccode	610	de
jgu.publisher.doi	10.1111/echo.14694
jgu.organisation.ror	https://ror.org/023b0x485
Appears in collections:	JGU-Publikationen

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