Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6230
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dc.contributor.authorTolba, Emad-
dc.contributor.authorWang, Xiaohong-
dc.contributor.authorWang, Shunfeng-
dc.contributor.authorNeufurth, Meik-
dc.contributor.authorAckermann, Maximilian-
dc.contributor.authorSchröder, Heinz C.-
dc.contributor.authorMüller, Werner E. G.-
dc.date.accessioned2021-08-03T08:32:49Z-
dc.date.available2021-08-03T08:32:49Z-
dc.date.issued2020-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/6240-
dc.description.abstractCement is used both as a construction material and for medical applications. Previously, it has been shown that the physiological polymer inorganic polyphosphate (polyP) is morphogenetically active in regeneration of skin, bone, and cartilage. The present study investigates the question if this polymer is also a suitable additive to improve the self-healing capacity not only of construction cement but also of inorganic bone void fillers. For the application in the cement, two different polyP-based amorphous nanoparticles (NP) are prepared, amorphous Ca-polyP NP and amorphous Ca-carbonate (ACC) NP. The particles are integrated into poly(methyl methacrylate) in a concentration ratio of 1:10. This material applied onto Portland cement blocks either by brush application or by blow spinning strongly accelerates the self-healing property of the cement after a 10 day incubation period. Most likely, this process depends on bacteria and their membrane-associated alkaline phosphatase, resulting in the formation of calcite from ACC. In a second approach, polyP is integrated into a calcium-silicate-based cement used in reconstitutive medicine. Subsequently, the cement becomes softer and more elastic. The data show that bioinspired polyP/ACC NP are suitable additives to improve the self-healing of construction cement and to biologize bone cement.en_GB
dc.language.isoengde
dc.rightsCC BY-NC-ND*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.ddc540 Chemiede_DE
dc.subject.ddc540 Chemistry and allied sciencesen_GB
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleAmorphous polyphosphate and Ca-carbonate nanoparticles improve the self-healing properties of both technical and medical cementsen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-6230-
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleBiotechnology journalde
jgu.journal.volume15de
jgu.journal.issue12de
jgu.pages.alternative2000101de
jgu.publisher.year2020-
jgu.publisher.nameWiley-VCHde
jgu.publisher.placeWeinheimde
jgu.publisher.urihttps://doi.org/10.1002/biot.202000101de
jgu.publisher.issn1860-7314de
jgu.organisation.placeMainz-
jgu.subject.ddccode540de
jgu.subject.ddccode610de
jgu.publisher.doi10.1002/biot.202000101
Appears in collections:JGU-Publikationen

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