Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-6177
Authors: Klett, Jan
Title: Structural motifs of alkali metal superbases in non-coordinating solvents
Online publication date: 6-Jul-2021
Language: english
Abstract: Lochmann–Schlosser superbases (LSB) are a standard reagent in synthetic chemistry to achieve an exchange of a proton on an organic framework with an alkali metal cation, which in turn can be replaced by a wide range of electrophilic groups. In standard examples, the deprotonating reagent consists of an equimolar mixture of n-butyllithium and potassium t-butoxide. However, the nature of the reactive species could not be pinned down either for this composition or for similar mixtures with comparable high reactivity. Despite the poor solubility and the fierce reactivity, some insights into this mixture were achieved by some indirect results, comparison with chemically related systems, or skillful deductions. Recent results, mainly based on new soluble compounds, delivered structural evidence. These new insights lead to advanced and more detailed conclusions about the interplay of the involved components.
DDC: 540 Chemie
540 Chemistry and allied sciences
Institution: Johannes Gutenberg-Universität Mainz
Department: FB 09 Chemie, Pharmazie u. Geowissensch.
Place: Mainz
DOI: http://doi.org/10.25358/openscience-6177
Version: Published version
Publication type: Zeitschriftenaufsatz
License: CC BY
Information on rights of use: https://creativecommons.org/licenses/by/4.0/
Journal: Chemistry - a European journal
27
3
Pages or article number: 888
904
Publisher: Wiley-VCH
Publisher place: Weinheim
Issue date: 2021
ISSN: 1521-3765
Publisher URL: https://doi.org/10.1002/chem.202002812
Publisher DOI: 10.1002/chem.202002812
Appears in collections:JGU-Publikationen

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