Please use this identifier to cite or link to this item: http://doi.org/10.25358/openscience-5506
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dc.contributor.authorReiner, Iris-
dc.contributor.authorTibubos, Ana N.-
dc.contributor.authorWerner, Antonia M.-
dc.contributor.authorErnst, Mareike-
dc.contributor.authorBrähler, Elmar-
dc.contributor.authorWiltink, Jörg-
dc.contributor.authorMichal, Matthias-
dc.contributor.authorSchulz, Andreas-
dc.contributor.authorWild, Philipp S.-
dc.contributor.authorMünzel, Thomas-
dc.contributor.authorArnold, Natalie-
dc.contributor.authorMahmoudpour, Seyed Hamidreza-
dc.contributor.authorLackner, Karl J.-
dc.contributor.authorPfeiffer, Norbert-
dc.contributor.authorBeutel, Manfred E.-
dc.date.accessioned2020-12-18T09:02:03Z-
dc.date.available2020-12-18T09:02:03Z-
dc.date.issued2020-
dc.identifier.urihttps://openscience.ub.uni-mainz.de/handle/20.500.12030/5510-
dc.description.abstractIn a large German community sample of adults, we investigated the association of chronic anxiousness with cardiovascular disease and mortality. Self-reported anxiousness from 11,643 German adults between 40 and 80 years of age from the Gutenberg Health Study (GHS) was analyzed over 5 years. Multivariable regression modeling assessed the relation between the variables, cardiovascular disease and mortality. Twelve percent of the participants reported consistently raised (chronic) anxiousness over at least 2.5 years. Anxiousness was more often reported by female, younger participants with a lower socioeconomic status, smokers and those with a family history of stroke and myocardial infarction. New onset of cardiovascular disease was linked to chronic anxiousness in men and new onset of anxiousness in women. However, chronic anxiousness did not predict all-cause mortality. Our results revealed that anxiousness is highly prevalent in German adults from middle to old age, affecting women in particular. In our study, we found sex-specific associations between new onset of cardiovascular disease and different forms of anxiousness in men and women. We suggest that even subclinical levels of anxiety need to be considered as cardiovascular risk factors. To elucidate potential harm of anxiousness for mental and physical health, we propose sex-specific analyses in further research studies, taking age and the course of anxiousness into account.en_GB
dc.description.sponsorshipDFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin Mainzde
dc.language.isoengde
dc.rightsCC BYde_DE
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subject.ddc610 Medizinde_DE
dc.subject.ddc610 Medical sciencesen_GB
dc.titleThe association of chronic anxiousness with cardiovascular disease and mortality in the community : results from the Gutenberg Health Studyen_GB
dc.typeZeitschriftenaufsatzde
dc.identifier.doihttp://doi.org/10.25358/openscience-5506-
jgu.type.contenttypeScientific articlede
jgu.type.dinitypearticleen_GB
jgu.type.versionPublished versionde
jgu.type.resourceTextde
jgu.organisation.departmentFB 04 Medizinde
jgu.organisation.number2700-
jgu.organisation.nameJohannes Gutenberg-Universität Mainz-
jgu.rights.accessrightsopenAccess-
jgu.journal.titleScientific Reportsde
jgu.journal.volume10de
jgu.pages.alternative12436de
jgu.publisher.year2020-
jgu.publisher.nameMacmillan Publishers Limited, part of Springer Naturede
jgu.publisher.placeLondonde
jgu.publisher.urihttps://doi.org/10.1038/s41598-020-69427-8de
jgu.publisher.issn2045-2322de
jgu.organisation.placeMainz-
jgu.subject.ddccode610de
jgu.publisher.doi10.1038/s41598-020-69427-8
Appears in collections:JGU-Publikationen

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